↓ Skip to main content

Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy

Overview of attention for article published in Gastroenterology, April 2012
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

twitter
2 X users
patent
1 patent

Citations

dimensions_citation
396 Dimensions

Readers on

mendeley
240 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Loss of Interleukin-10 Signaling and Infantile Inflammatory Bowel Disease: Implications for Diagnosis and Therapy
Published in
Gastroenterology, April 2012
DOI 10.1053/j.gastro.2012.04.045
Pubmed ID
Authors

Daniel Kotlarz, Rita Beier, Dhaarini Murugan, Jana Diestelhorst, Ole Jensen, Kaan Boztug, Dietmar Pfeifer, Hans Kreipe, Eva–Doreen Pfister, Ulrich Baumann, Jacek Puchalka, Jens Bohne, Odul Egritas, Buket Dalgic, Kaija–Leena Kolho, Axel Sauerbrey, Stephan Buderus, Tayfun Güngör, Axel Enninger, Yu Kar Ling Koda, Graziella Guariso, Batia Weiss, Selim Corbacioglu, Piotr Socha, Nuray Uslu, Ayse Metin, Ghassan T. Wahbeh, Khalid Husain, Dina Ramadan, Waleed Al–Herz, Bodo Grimbacher, Martin Sauer, Karl–Walter Sykora, Sibylle Koletzko, Christoph Klein

Abstract

Homozygous loss of function mutations in interleukin-10 (IL10) and interleukin-10 receptors (IL10R) cause severe infantile (very early onset) inflammatory bowel disease (IBD). Allogeneic hematopoietic stem cell transplantation (HSCT) was reported to induce sustained remission in 1 patient with IL-10R deficiency. We investigated heterogeneity among patients with very early onset IBD, its mechanisms, and the use of allogeneic HSCT to treat this disorder.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 1 <1%
Australia 1 <1%
Unknown 238 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 55 23%
Researcher 41 17%
Student > Master 30 13%
Student > Doctoral Student 16 7%
Student > Bachelor 16 7%
Other 40 17%
Unknown 42 18%
Readers by discipline Count As %
Medicine and Dentistry 76 32%
Agricultural and Biological Sciences 40 17%
Immunology and Microbiology 28 12%
Biochemistry, Genetics and Molecular Biology 27 11%
Psychology 5 2%
Other 18 8%
Unknown 46 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2014.
All research outputs
#7,777,586
of 25,371,288 outputs
Outputs from Gastroenterology
#5,555
of 12,315 outputs
Outputs of similar age
#52,348
of 175,819 outputs
Outputs of similar age from Gastroenterology
#54
of 158 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 12,315 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,819 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.