Title |
Use of HbA1c in Screening for Cuban-Americans with Undiagnosed Type 2 Diabetes
|
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Published in |
Journal of Immigrant and Minority Health, June 2010
|
DOI | 10.1007/s10903-010-9363-3 |
Pubmed ID | |
Authors |
Fatma G. Huffman, Joel C. Exebio, Gustavo G. Zarini, Cristobal Exebio |
Abstract |
This study evaluated the use of HbA(1c) as a screening tool for undiagnosed type 2 diabetes (fasting plasma glucose ≥7.0 mmol/l) in a sample of Cuban-Americans aged ≥ 30 years old. Subjects were randomly recruited from Miami-Dade and Broward counties, FL. Fasting plasma glucose was measured by hexokinase enzymatic method. HbA(1c) was measured by the DCA2000 + system using the monoclonal antibody method. HbA(1c) demonstrated a high predictive value in detecting undiagnosed diabetes. The area under the receiver operating characteristics (ROC) curve was 0.87. Also, HbA(1c) had high sensitivity and specificity when using a cut off value of 6.37 (71 and 86%, respectively). Moderate sensitivity and very high specificity were shown with a cut off value of 6.84 (57 and 96%, respectively). HbA(1c) is a reliable alternative to fasting plasma glucose in screening for undiagnosed diabetes in Cuban-Americans. |
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