| Title |
TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals
|
|---|---|
| Published in |
Diabetologia, August 2012
|
| DOI | 10.1007/s00125-012-2660-8 |
| Pubmed ID | |
| Authors |
O. Le Bacquer, J. Kerr-Conte, S. Gargani, N. Delalleau, M. Huyvaert, V. Gmyr, P. Froguel, B. Neve, F. Pattou |
| Abstract |
Transcription factor 7-like 2 (TCF7L2) is a Wnt-signalling-associated transcription factor. Genetic studies have clearly demonstrated that DNA polymorphisms within TCF7L2 confer the strongest known association with increased risk of type 2 diabetes. However, the impact of the TCF7L2 type-2-diabetes-associated rs7903146 T allele on biological function and morphology of human pancreatic islets is unknown. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 3% |
| South Africa | 1 | 3% |
| Unknown | 31 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 33% |
| Researcher | 5 | 15% |
| Student > Master | 5 | 15% |
| Student > Bachelor | 3 | 9% |
| Professor | 2 | 6% |
| Other | 4 | 12% |
| Unknown | 3 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 30% |
| Medicine and Dentistry | 10 | 30% |
| Biochemistry, Genetics and Molecular Biology | 7 | 21% |
| Nursing and Health Professions | 1 | 3% |
| Arts and Humanities | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 3 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2012.
All research outputs
#14,605,487
of 22,675,759 outputs
Outputs from Diabetologia
#4,358
of 5,025 outputs
Outputs of similar age
#102,885
of 169,209 outputs
Outputs of similar age from Diabetologia
#40
of 67 outputs
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We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.