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The burden of community‐managed acute respiratory infections in the first 2‐years of life

Overview of attention for article published in Pediatric Pulmonology, May 2016
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Title
The burden of community‐managed acute respiratory infections in the first 2‐years of life
Published in
Pediatric Pulmonology, May 2016
DOI 10.1002/ppul.23480
Pubmed ID
Authors

Mohinder Sarna, Robert S. Ware, Theo P. Sloots, Michael D. Nissen, Keith Grimwood, Stephen B. Lambert

Abstract

Contemporary information on acute respiratory infections (ARIs) in children is based on hospital cohorts, primary healthcare presentations, and high-risk birth cohort studies. We describe the burden and determinants of symptomatic episodes of ARIs in unselected healthy infants in the first 2-years of life. One hundred and fifty-four infants from subtropical Brisbane, Australia participated in a longitudinal, community-based birth cohort study. A daily tick-box diary captured pre-defined respiratory symptoms. Parents also completed a burden diary, recording family physician and hospital visits, and antibiotic use. Participants contributed 88,032 child-days (78.2% of expected), of which 17,316 (19.7%) days were symptomatic during 1,651 ARI episodes: incidence rate 0.56 ARIs per child-month (95%CI: 0.54, 0.59). Runny nose (14,220 days; 6.0-days median duration) and dry cough (6,880 days; 4.0-days median duration) were reported most frequently. Overall, 955 burden diaries recorded 455 family physician visits (1-8 visits per ARI) and 48 hospital presentations, including six hospital admissions. Antibiotics were prescribed on 209 occasions (21.9% of ARI episodes where burden diary submitted). Increasing age, non-summer seasons, and attendance at childcare were associated with an increased risk of ARI. ARIs are a common cause of morbidity in the first 2-years of life, with children experiencing 13 discrete ARI episodes and almost 5-months of respiratory symptoms. Most ARIs are managed in the community by parents and family physicians. Antibiotic prescribing remains common for ARIs in young children. Secular societal changes, including greater use of childcare in early childhood, may have maintained the high ARI incidence in this age-group. Pediatr Pulmonol. 2016; 9999:XX-XX. © 2016 Wiley Periodicals, Inc.

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Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Student > Bachelor 8 13%
Student > Ph. D. Student 7 11%
Researcher 6 9%
Other 6 9%
Other 10 16%
Unknown 16 25%
Readers by discipline Count As %
Medicine and Dentistry 26 41%
Nursing and Health Professions 6 9%
Social Sciences 3 5%
Psychology 2 3%
Agricultural and Biological Sciences 2 3%
Other 7 11%
Unknown 18 28%