| Title |
Vermamoeba vermiformis-Aspergillus fumigatus relationships and comparison with other phagocytic cells
|
|---|---|
| Published in |
Parasitology Research, July 2016
|
| DOI | 10.1007/s00436-016-5182-3 |
| Pubmed ID | |
| Authors |
Elodie Maisonneuve, Estelle Cateau, Sihem Kaaki, Marie-Hélène Rodier |
| Abstract |
Free living amoebae (FLA) are protists ubiquitously present in the environment. Aspergillus fumigatus is a mould responsible for severe deep-seated infections, and that can be recovered in the same habitats as the FLA. By conducting coculture experiments and fungal incubation with amoebal supernatants, we report herein that Vermamoeba vermiformis, a FLA present in hospital water systems, promotes filamentation and growth of A. fumigatus. This finding is of particular importance to institutions whose water systems might harbor FLA and could potentially be used by immunocompromised patients. Also, the relationships between V. vermiformis and A. fumigatus were compared to those between this fungus and two other phagocytic cells: Acanthamoeba castellanii, another FLA, and macrophage-like THP-1 cells. After 4 h of coincubation, the percentages of the three phagocytic cell types with adhered conidia were similar, even though the types of receptors between FLA and macrophagic cell seemed different. However, the percentage of THP-1 with internalized conidia was considerably lower (40 %) in comparison with the two other cell types (100 %). Thus, this study revealed that interactions between A. fumigatus and these three phagocytic cell types show similarities, even though it is premature to extrapolate these results to interpret relationships between A. fumigatus and macrophages. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 6% |
| Unknown | 17 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 28% |
| Student > Master | 4 | 22% |
| Student > Bachelor | 2 | 11% |
| Student > Doctoral Student | 1 | 6% |
| Professor | 1 | 6% |
| Other | 3 | 17% |
| Unknown | 2 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 5 | 28% |
| Biochemistry, Genetics and Molecular Biology | 3 | 17% |
| Agricultural and Biological Sciences | 3 | 17% |
| Medicine and Dentistry | 3 | 17% |
| Earth and Planetary Sciences | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 2 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2016.
All research outputs
#16,402,928
of 24,164,942 outputs
Outputs from Parasitology Research
#1,880
of 3,898 outputs
Outputs of similar age
#233,408
of 362,050 outputs
Outputs of similar age from Parasitology Research
#31
of 87 outputs
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