| Title |
Neuroinflammation, Neuroautoimmunity, and the Co-Morbidities of Complex Regional Pain Syndrome
|
|---|---|
| Published in |
Journal of Neuroimmune Pharmacology, August 2012
|
| DOI | 10.1007/s11481-012-9392-x |
| Pubmed ID | |
| Authors |
Mark S. Cooper, Vincent P. Clark |
| Abstract |
Complex Regional Pain Syndrome (CRPS) is associated with non-dermatomal patterns of pain, unusual movement disorders, and somatovisceral dysfunctions. These symptoms are viewed by some neurologists and psychiatrists as being psychogenic in origin. Recent evidence, however, suggests that an autoimmune attack on self-antigens found in the peripheral and central nervous system may underlie a number of CRPS symptoms. From both animal and human studies, evidence is accumulating that neuroinflammation can spread, either anterograde or retrograde, via axonal projections in the CNS, thereby establishing neuroinflammatory tracks and secondary neuroinflammatory foci within the neuraxis. These findings suggest that neuroinflammatory lesions, as well as their associated functional consequences, should be evaluated during the differential diagnosis of non-dermatomal pain presentations, atypical movement disorders, as well as other "medically unexplained symptoms", which are often attributed to psychogenic illness. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 60% |
| United Kingdom | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 90% |
| Scientists | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | 3% |
| United Kingdom | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 75 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 11 | 14% |
| Researcher | 11 | 14% |
| Student > Master | 11 | 14% |
| Student > Ph. D. Student | 10 | 13% |
| Student > Bachelor | 8 | 10% |
| Other | 21 | 27% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 40 | 51% |
| Neuroscience | 9 | 11% |
| Agricultural and Biological Sciences | 4 | 5% |
| Nursing and Health Professions | 3 | 4% |
| Psychology | 3 | 4% |
| Other | 9 | 11% |
| Unknown | 11 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2020.
All research outputs
#1,917,813
of 24,217,893 outputs
Outputs from Journal of Neuroimmune Pharmacology
#54
of 583 outputs
Outputs of similar age
#11,949
of 172,054 outputs
Outputs of similar age from Journal of Neuroimmune Pharmacology
#3
of 11 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 583 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done particularly well, scoring higher than 90% of its peers.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.