| Title |
Neuroinflammation, Neurodegeneration, and Depression
|
|---|---|
| Published in |
Neurotoxicity Research, August 2012
|
| DOI | 10.1007/s12640-012-9348-1 |
| Pubmed ID | |
| Authors |
Laura L. Hurley, Yousef Tizabi |
| Abstract |
Neurodegeneration and depression are two common co-morbid conditions, particularly within the aging population. Research has linked neuroinflammation as a major contributing factor to both of these diseases. The key to neuroinflammation effects on neurodegeneration and depression appears to lie within the dysregulation of the control and release of pro- and anti-inflammatory cytokines. This can come from an internal or external insult to the system, or from changes in the individual due to aging that culminate in immune dysregulation. The need to reduce neuroinflammation has led to extensive research into neuroprotectants. We discuss the efficacy found with nicotine, alcohol, resveratrol, curcumin, and ketamine. Our main focus will be on what research tells us about the connections between neuroinflammation, neurodegeneration, and depression, and the hope that neuroprotectants research gives people suffering from neurodegeneration and depression stemming from neuroinflammation. We will conclude by making suggestions for future research in this area. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 20% |
| United Kingdom | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 276 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Portugal | 1 | <1% |
| Brazil | 1 | <1% |
| Netherlands | 1 | <1% |
| Peru | 1 | <1% |
| Belarus | 1 | <1% |
| Unknown | 269 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 43 | 16% |
| Student > Bachelor | 42 | 15% |
| Student > Ph. D. Student | 41 | 15% |
| Researcher | 27 | 10% |
| Student > Doctoral Student | 14 | 5% |
| Other | 46 | 17% |
| Unknown | 63 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 48 | 17% |
| Agricultural and Biological Sciences | 42 | 15% |
| Medicine and Dentistry | 36 | 13% |
| Biochemistry, Genetics and Molecular Biology | 18 | 7% |
| Psychology | 16 | 6% |
| Other | 35 | 13% |
| Unknown | 81 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2023.
All research outputs
#2,453,379
of 25,397,764 outputs
Outputs from Neurotoxicity Research
#59
of 926 outputs
Outputs of similar age
#15,022
of 174,047 outputs
Outputs of similar age from Neurotoxicity Research
#2
of 4 outputs
Altmetric has tracked 25,397,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 926 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,047 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.