| Title |
Right ventricular regional and global systolic function is diminished in patients with pulmonary arterial hypertension: a 2-dimensional ultrasound speckle tracking echocardiography study
|
|---|---|
| Published in |
The International Journal of Cardiovascular Imaging, September 2012
|
| DOI | 10.1007/s10554-012-0114-5 |
| Pubmed ID | |
| Authors |
Yuman Li, Mingxing Xie, Xinfang Wang, Qing Lu, Manli Fu |
| Abstract |
The purpose of the study is to evaluate right ventricular (RV) regional and global systolic function in patients with pulmonary arterial hypertension (PAH) by 2-dimensional ultrasound speckle tracking echocardiography (STE) and explore the impact of pulmonary artery systolic pressure (PASP) and pulmonary vascular resistance (PVR) on RV systolic function. 42 patients with PAH and 31 healthy controls were included in this study. RV longitudinal peak systolic strain (LS) and strain rate (LSRs) were measured at the basal, mid and apical segments of the RV free wall and septum by STE. RV global longitudinal peak systolic strain (GLS) and strain rate (GLSRs) were also measured by STE. RV ejection fraction (EF) was determinated by cardiac magnetic resonance (CMR) imaging. LS and LSRs of RV 6 segments were significantly reduced in patients with PAH compared with controls. RV GLS and GLSRs were lower in patients with varying degrees of PAH than controls. Furthermore, RV GLS were most altered in patients with severe PAH compared with mild PAH. PVR was correlated with RV GLS and GLSRs (r₁ = -0.549; r₂ = -0.466, respectively, P < 0.05). Similarly, there was correlation between PASP and RV GLS and GLSRs (r₁ = -0.551; r₂ = -0.425, respectively, P < 0.05). GLS and GLSRs were correlated with CMR-derived RVEF. (r₁ = 0.693; r₂ = 0.560, respectively, P < 0.05). STE can identify impaired RV regional and global systolic function in patients with PAH. STE-derived strain and strain rate can be used as novel indices for RV function assessment from 2-dimensional echocardiographic images. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 46 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 20% |
| Student > Doctoral Student | 7 | 15% |
| Student > Master | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Researcher | 4 | 9% |
| Other | 9 | 20% |
| Unknown | 8 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 59% |
| Veterinary Science and Veterinary Medicine | 2 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Computer Science | 1 | 2% |
| Agricultural and Biological Sciences | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 12 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2012.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from The International Journal of Cardiovascular Imaging
#1,460
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Outputs of similar age
#168,349
of 186,940 outputs
Outputs of similar age from The International Journal of Cardiovascular Imaging
#10
of 31 outputs
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