| Title |
TCF7L2 promotes beta cell regeneration in human and mouse pancreas
|
|---|---|
| Published in |
Diabetologia, September 2012
|
| DOI | 10.1007/s00125-012-2693-z |
| Pubmed ID | |
| Authors |
L. Shu, K. Zien, G. Gutjahr, J. Oberholzer, F. Pattou, J. Kerr-Conte, K. Maedler |
| Abstract |
Diabetes is characterised by loss and dysfunction of the beta cell. A major goal of diabetes therapy is to promote the formation of new beta cells. Polymorphisms of T cell factor 7-like 2 (TCF7L2) are associated with type 2 diabetes, negatively regulating beta cell survival and function. Here, we provide evidence for a role of TCF7L2 in beta cell proliferation and regeneration. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Unknown | 51 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 25% |
| Student > Ph. D. Student | 9 | 17% |
| Professor | 5 | 10% |
| Professor > Associate Professor | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 9 | 17% |
| Unknown | 8 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 35% |
| Medicine and Dentistry | 12 | 23% |
| Biochemistry, Genetics and Molecular Biology | 10 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Arts and Humanities | 1 | 2% |
| Other | 0 | 0% |
| Unknown | 10 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2012.
All research outputs
#14,606,450
of 22,678,224 outputs
Outputs from Diabetologia
#4,358
of 5,025 outputs
Outputs of similar age
#102,113
of 169,085 outputs
Outputs of similar age from Diabetologia
#42
of 67 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,025 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,085 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.