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Self-contained microfluidic systems: a review

Overview of attention for article published in Lab on a Chip - Miniaturisation for Chemistry & Biology, January 2016
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Title
Self-contained microfluidic systems: a review
Published in
Lab on a Chip - Miniaturisation for Chemistry & Biology, January 2016
DOI 10.1039/c6lc00712k
Pubmed ID
Authors

Mitchell Boyd-Moss, Sara Baratchi, Martina Di Venere, Khashayar Khoshmanesh

Abstract

Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and health conditions using small amounts of biological samples and reagents. Despite these remarkable features, conventional microfluidic systems rely on bulky expensive external equipment, which hinders their utility as powerful analysis tools outside of research laboratories. 'Self-contained' microfluidic systems, which contain all necessary components to facilitate a complete assay, have been developed to address this limitation. In this review, we provide an in-depth overview of self-contained microfluidic systems. We categorise these systems based on their operating mechanisms into three major groups: passive, hand-powered and active. Several examples are provided to discuss the structure, capabilities and shortcomings of each group. In particular, we discuss the self-contained microfluidic systems enabled by active mechanisms, due to their unique capability for running multi-step and highly controllable diagnostic assays. Integration of self-contained microfluidic systems with the image acquisition and processing capabilities of smartphones, especially those equipped with accessory optical components, enables highly sensitive and quantitative assays, which are discussed. Finally, the future trends and possible solutions to expand the versatility of self-contained, stand-alone microfluidic platforms are outlined.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 244 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Austria 1 <1%
Hong Kong 1 <1%
Canada 1 <1%
Brazil 1 <1%
Unknown 237 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 63 26%
Researcher 39 16%
Student > Master 28 11%
Student > Bachelor 22 9%
Student > Doctoral Student 18 7%
Other 30 12%
Unknown 44 18%
Readers by discipline Count As %
Engineering 88 36%
Biochemistry, Genetics and Molecular Biology 24 10%
Agricultural and Biological Sciences 23 9%
Chemistry 21 9%
Physics and Astronomy 7 3%
Other 27 11%
Unknown 54 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2016.
All research outputs
#20,970,494
of 25,756,911 outputs
Outputs from Lab on a Chip - Miniaturisation for Chemistry & Biology
#5,022
of 5,997 outputs
Outputs of similar age
#297,478
of 401,844 outputs
Outputs of similar age from Lab on a Chip - Miniaturisation for Chemistry & Biology
#292
of 356 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,997 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 401,844 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 356 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.