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Neurocognitive Predictors of ADHD Outcome: a 6-Year Follow-up Study

Overview of attention for article published in Research on Child and Adolescent Psychopathology, July 2016
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Title
Neurocognitive Predictors of ADHD Outcome: a 6-Year Follow-up Study
Published in
Research on Child and Adolescent Psychopathology, July 2016
DOI 10.1007/s10802-016-0175-3
Pubmed ID
Authors

Marloes van Lieshout, Marjolein Luman, Jos W. R. Twisk, Stephen V. Faraone, Dirk J. Heslenfeld, Catharina A. Hartman, Pieter J. Hoekstra, Barbara Franke, Jan K. Buitelaar, Nanda N. J. Rommelse, Jaap Oosterlaan

Abstract

Although a broad array of neurocognitive dysfunctions are associated with ADHD, it is unknown whether these dysfunctions play a role in the course of ADHD symptoms. The present longitudinal study investigated whether neurocognitive functions assessed at study-entry (mean age = 11.5 years, SD = 2.7) predicted ADHD symptom severity and overall functioning 6 years later (mean age = 17.4 years, 82.6 % = male) in a carefully phenotyped large sample of 226 Caucasian participants from 182 families diagnosed with ADHD-combined type. Outcome measures were dimensional measures of ADHD symptom severity and the Kiddie-Global Assessment Scale (K-GAS) for overall functioning. Predictors were derived from component scores for 8 domains of neurocognitive functioning: working memory, motor inhibition, cognitive inhibition, reaction time variability, timing, information processing speed, motor control, intelligence. Effects of age, gender, and pharmacological treatment were considered. Results showed that better working memory predicted lower ADHD symptom severity (R (2)  = 3.0 %), and less reaction time variability predicted better overall functioning (higher K-GAS-score, R (2)  = 5.6 %). Predictors were still significant with baseline behavior included in the models. The role of neurocognitive functioning in the long term outcome of ADHD behavior is discussed.

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Mendeley readers

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Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Switzerland 1 <1%
Unknown 186 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 31 16%
Student > Ph. D. Student 26 14%
Researcher 23 12%
Student > Doctoral Student 18 10%
Student > Bachelor 18 10%
Other 32 17%
Unknown 41 22%
Readers by discipline Count As %
Psychology 70 37%
Neuroscience 19 10%
Medicine and Dentistry 18 10%
Nursing and Health Professions 7 4%
Agricultural and Biological Sciences 3 2%
Other 19 10%
Unknown 53 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2016.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Research on Child and Adolescent Psychopathology
#1,848
of 2,047 outputs
Outputs of similar age
#286,733
of 370,065 outputs
Outputs of similar age from Research on Child and Adolescent Psychopathology
#17
of 25 outputs
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