| Title |
Prospective evaluation of voice outcome during the first two years in male patients treated by radiotherapy or laser surgery for T1a glottic carcinoma
|
|---|---|
| Published in |
European Archives of Oto-Rhino-Laryngology, February 2012
|
| DOI | 10.1007/s00405-012-1947-1 |
| Pubmed ID | |
| Authors |
Christine D. L. van Gogh, Irma M. Verdonck-de Leeuw, Jeanne Wedler-Peeters, Johannes A. Langendijk, Hans F. Mahieu |
| Abstract |
In this prospective cohort study, we assessed voice outcome in patients before and up to 2 years after treatment for early glottic cancer either by radiotherapy or by laser surgery; 106 male patients, treated for T1aN0M0 glottic cancer either by endoscopic laser surgery (n = 67) or by radiotherapy (n = 39), participated in the study. Patients' voices were recorded and analysed pre-treatment and 3, 6, 12 and 24 months post-treatment at their routine visit at the outpatient clinic. Average fundamental frequency (F0), percent jitter, percent shimmer and normalized noise energy (NNE) were determined. After 2 years, local control rate was 95% in the radiotherapy group and 97% in the laser surgery group. Larynx preservation rate was 95% after radiotherapy and 100% after laser surgery. Voice outcome recovers more quickly in patients treated with laser surgery in comparison to radiotherapy: 3 months after laser surgery there is no longer a difference with regard to normal voices except for the fundamental frequency, which remains higher pitched, even in the longer term. For patients treated with radiotherapy it takes longer for jitter, shimmer and NNE to become normal, where jitter remains significantly different from normal voices even after 2 years. According to these results, we believe that laser surgery is the first treatment of choice in the treatment of selected cases of T1a glottic carcinomas with good functional and oncological results. |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 2% |
| Unknown | 55 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 14% |
| Other | 7 | 13% |
| Researcher | 7 | 13% |
| Student > Bachelor | 7 | 13% |
| Student > Postgraduate | 5 | 9% |
| Other | 17 | 30% |
| Unknown | 5 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 68% |
| Agricultural and Biological Sciences | 3 | 5% |
| Nursing and Health Professions | 1 | 2% |
| Computer Science | 1 | 2% |
| Arts and Humanities | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 8 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2016.
All research outputs
#6,381,374
of 22,678,224 outputs
Outputs from European Archives of Oto-Rhino-Laryngology
#325
of 3,036 outputs
Outputs of similar age
#58,591
of 247,829 outputs
Outputs of similar age from European Archives of Oto-Rhino-Laryngology
#4
of 32 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 3,036 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,829 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.