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Insight into rheumatological cause and effect through the use of Mendelian randomization

Overview of attention for article published in Nature Reviews Rheumatology, July 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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1 news outlet
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25 X users
peer_reviews
1 peer review site

Citations

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48 Dimensions

Readers on

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64 Mendeley
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Title
Insight into rheumatological cause and effect through the use of Mendelian randomization
Published in
Nature Reviews Rheumatology, July 2016
DOI 10.1038/nrrheum.2016.102
Pubmed ID
Authors

Philip C. Robinson, Hyon K. Choi, Ron Do, Tony R. Merriman

Abstract

Establishing causality of risk factors is important to determine the pathogenetic mechanisms underlying rheumatic diseases, and can facilitate the design of interventions to improve care for affected patients. The presence of unmeasured confounders, as well as reverse causation, is a challenge to the assignment of causality in observational studies. Alleles for genetic variants are randomly inherited at meiosis. Mendelian randomization analysis uses these genetic variants to test whether a particular risk factor is causal for a disease outcome. In this Review of the Mendelian randomization technique, we discuss published results and potential applications in rheumatology, as well as the general clinical utility and limitations of the approach.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Unknown 62 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 22%
Student > Bachelor 10 16%
Student > Ph. D. Student 8 13%
Student > Master 5 8%
Other 4 6%
Other 12 19%
Unknown 11 17%
Readers by discipline Count As %
Medicine and Dentistry 21 33%
Biochemistry, Genetics and Molecular Biology 12 19%
Agricultural and Biological Sciences 8 13%
Mathematics 2 3%
Computer Science 2 3%
Other 4 6%
Unknown 15 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2021.
All research outputs
#1,586,886
of 25,196,456 outputs
Outputs from Nature Reviews Rheumatology
#353
of 2,407 outputs
Outputs of similar age
#28,897
of 364,239 outputs
Outputs of similar age from Nature Reviews Rheumatology
#8
of 53 outputs
Altmetric has tracked 25,196,456 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,407 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,239 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.