↓ Skip to main content

Quantitative analysis of MRI signal intensity in new variant Creutzfeldt-Jakob disease.

Overview of attention for article published in British Journal of Radiology, January 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

policy
1 policy source
patent
1 patent

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
17 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Quantitative analysis of MRI signal intensity in new variant Creutzfeldt-Jakob disease.
Published in
British Journal of Radiology, January 2014
DOI 10.1259/bjr.72.860.10624339
Pubmed ID
Authors

A Coulthard, K Hall, P T English, P G Ince, D J Burn, D Bates

Abstract

High signal intensity within the posterior thalamus (pulvinar nucleus) has been noted on MRI in patients with new variant Creutzfeldt-Jakob disease (nvCJD). In this study MRI examinations from three patients with proven nvCJD were compared with MRI examinations from a control group of 14 age-matched subjects with no neurological abnormalities. Mean signal intensity from seven target areas (periaqueductal tissue, posterior thalamus, dorsomedial thalamus, anterior thalamus, putamen, caudate head and frontal white matter) was calculated in each case. Absolute signal intensity measurements were not significantly different between the groups. Patients with nvCJD showed significantly higher signal intensity within dorsomedial thalamus, posterior thalamus and periaqueductal region than control patients when these measurements were normalized to the signal intensity of normal appearing white matter. Highly significant differences in posterior thalamus/putamen signal intensity ratio (PPR) and posterior thalamus/caudate ratio (PCR) were observed between the groups. For proton density images, PPR and PCR were greater than 1 for all nvCJD patients and less than 1 for all control patients. Both PPR and PCR are simple to calculate and offer a simple, non-invasive indicator of nvCJD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 24%
Student > Ph. D. Student 4 24%
Other 3 18%
Professor 2 12%
Professor > Associate Professor 2 12%
Other 1 6%
Unknown 1 6%
Readers by discipline Count As %
Medicine and Dentistry 7 41%
Biochemistry, Genetics and Molecular Biology 2 12%
Engineering 2 12%
Neuroscience 2 12%
Immunology and Microbiology 1 6%
Other 2 12%
Unknown 1 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2012.
All research outputs
#5,448,088
of 25,377,790 outputs
Outputs from British Journal of Radiology
#447
of 3,297 outputs
Outputs of similar age
#61,376
of 322,947 outputs
Outputs of similar age from British Journal of Radiology
#89
of 794 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,297 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,947 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 794 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.