Title |
Efficacy of a Fish Protein Hydrolysate in Malnourished Children
|
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Published in |
Indian Journal of Clinical Biochemistry, July 2011
|
DOI | 10.1007/s12291-011-0145-z |
Pubmed ID | |
Authors |
Knut Olav Nesse, A. P. Nagalakshmi, P. Marimuthu, Mamta Singh |
Abstract |
Protein hydrolysates are good nutritional supplements as their bioactive ingredients can be easily absorbed and utilized for various metabolic activities. A fish protein hydrolysate (Amizate), prepared by a unique process of hydrolysis has the advantage of high di/tri peptide content (<10 kDa) along with essential and non essential amino acids, micronutrients and vitamins. The effect of Amizate on malnourished children (6-8 years, a total of 438) of Grade I and II (Gomez's classification) with respect to immunoglobulins, CD4/CD8 ratios and hemoglobin was examined. Measurement of these parameters during the user trial study (at the beginning and the end after 4 months) indicated that the levels of the immunological parameters were not significantly altered by the Amizate treatment. The values of immunoglobulins and CD4/CD8 ratios of malnourished children (India) are in the normal range and are in accordance with the reported values of various ethnic groups. |
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