| Title |
Smoking and survival after breast cancer diagnosis: a prospective observational study and systematic review
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, September 2012
|
| DOI | 10.1007/s10549-012-2276-1 |
| Pubmed ID | |
| Authors |
Dejana Braithwaite, Monika Izano, Dan H. Moore, Marilyn L. Kwan, Martin C. Tammemagi, Robert A. Hiatt, Karla Kerlikowske, Candyce H. Kroenke, Carol Sweeney, Laurel Habel, Adrienne Castillo, Erin Weltzien, Bette Caan |
| Abstract |
The association of smoking with outcomes following breast cancer prognosis is not well understood. In a cohort study called Life After Cancer Epidemiology (LACE), 2,265 women diagnosed with breast cancer were followed for a median of 12 years. We used multivariable proportional-hazards models to determine whether smoking, assessed approximately two years post-diagnosis, was associated with risk of death among these women. We also undertook a systematic review of all cohort studies to date that have examined the association between smoking and breast cancer mortality. Compared with never smokers, women who were current smokers had a twofold higher rate of dying from breast cancer [hazard ratio (HR) = 2.01, 95 % confidence interval (CI) 1.27-3.18] and an approximately fourfold higher rate of dying from competing (non-breast cancer) causes (HR = 3.84, 95 % CI 2.50-5.89). Among seven studies that met the inclusion criteria in the systematic review, three studies and our own reported significantly increased risk of breast cancer death with current smoking. We found little evidence of an association between former smoking and breast cancer mortality (HR = 1.24, 95 % CI 0.94-1.64). Consistent with findings from our prospective observational study, the systematic review of seven additional studies indicates positive association of current smoking with breast cancer mortality, but weak association with former smoking. Women who smoke following breast cancer diagnosis and treatment are at higher risk of death both from breast cancer and other causes. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 59 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 13% |
| Other | 6 | 10% |
| Student > Doctoral Student | 5 | 8% |
| Professor | 5 | 8% |
| Student > Ph. D. Student | 4 | 7% |
| Other | 13 | 21% |
| Unknown | 20 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 41% |
| Agricultural and Biological Sciences | 5 | 8% |
| Social Sciences | 3 | 5% |
| Business, Management and Accounting | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 21 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2015.
All research outputs
#12,569,781
of 22,679,690 outputs
Outputs from Breast Cancer Research and Treatment
#2,708
of 4,618 outputs
Outputs of similar age
#87,975
of 172,058 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#34
of 62 outputs
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We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.