Title |
Novel concepts in male factor infertility: clinical and laboratory perspectives
|
---|---|
Published in |
Journal of Assisted Reproduction and Genetics, July 2016
|
DOI | 10.1007/s10815-016-0763-8 |
Pubmed ID | |
Authors |
Sandro C. Esteves |
Abstract |
In recent years, the management of male factor infertility has undergone important changes with the introduction of novel concepts, advanced testing, and therapeutic interventions. This review highlights some of these changes and discusses their impact to routine clinical practice. First, we discuss the recent changes in the World Health Organization (WHO) laboratory methods and reference values for the examination of human semen. Second, we examine the role of sperm chromatin integrity tests in light of increasing evidence of the detrimental effect of sperm DNA fragmentation on reproductive outcomes. Third, we summarize the main findings of varicocele-related infertility and the outcomes of microsurgical varicocele repair to different case scenarios. Lastly, we critically discuss the current management of men with nonobstructive azoospermia seeking fertility and the new opportunities that emerged to help these men achieve biological fatherhood. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 33% |
France | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Denmark | 1 | <1% |
Unknown | 151 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 24 | 16% |
Student > Bachelor | 22 | 14% |
Student > Ph. D. Student | 16 | 11% |
Researcher | 13 | 9% |
Other | 10 | 7% |
Other | 27 | 18% |
Unknown | 40 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 45 | 30% |
Biochemistry, Genetics and Molecular Biology | 23 | 15% |
Agricultural and Biological Sciences | 21 | 14% |
Nursing and Health Professions | 6 | 4% |
Engineering | 3 | 2% |
Other | 11 | 7% |
Unknown | 43 | 28% |