Title |
Flavonol triglycoside and investigation of the antioxidant and cell stimulating activities of Annona muricata Linn.
|
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Published in |
Archives of Pharmacal Research, May 2012
|
DOI | 10.1007/s12272-012-0501-4 |
Pubmed ID | |
Authors |
Mahmoud Nawwar, Nahla Ayoub, Sahar Hussein, Amani Hashim, Reham El-Sharawy, Kristian Wende, Manuela Harms, Ulrike Lindequist |
Abstract |
Chemical investigation on leaves of Annona muricata resulted in the isolation of the flavonol triglycoside, quercetin 3-O-α-rhamnosyl-(1″″ → 6″)-β-sophoroside, together with twelve known phenolics. The structures of these compounds were established by 1D- and 2D-nuclear magnetic resonance spectroscopic techniques and mass spectrometry data. The in vitro antioxidant studies of the investigated aqueous ethanol extract and its column fractions were accomplished using the oxygen radical absorbance capacity (ORAC) method. A stimulating effect on HaCaT human keratinocytes by the leaf extract was also assessed. Il-6 production after UV irradiation was not influenced by A. muricata leaf extract. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Malaysia | 1 | <1% |
United States | 1 | <1% |
Unknown | 147 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 29 | 19% |
Researcher | 15 | 10% |
Student > Master | 12 | 8% |
Student > Postgraduate | 9 | 6% |
Student > Ph. D. Student | 6 | 4% |
Other | 24 | 16% |
Unknown | 54 | 36% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 21 | 14% |
Chemistry | 19 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 18 | 12% |
Biochemistry, Genetics and Molecular Biology | 13 | 9% |
Medicine and Dentistry | 10 | 7% |
Other | 7 | 5% |
Unknown | 61 | 41% |