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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites
|
|---|---|
| Published in |
Molecular Immunology, October 2012
|
| DOI | 10.1016/j.molimm.2012.08.015 |
| Pubmed ID | |
| Authors |
Igor Cestari, Ingrid Evans-Osses, Luregn J. Schlapbach, Iara de Messias-Reason, Marcel I. Ramirez |
| Abstract |
Studies in the past decade have demonstrated a crucial role for the complement lectin pathway in host defence against protozoan microbes. Recognition of pathogen surface molecules by mannan-binding lectin and ficolins revealed new mechanisms of innate immune defence and a diversity of parasite strategies of immune evasion. In the present review, we will discuss the current knowledge of: (1) the molecular mechanism of lectin pathway activation by trypanosomes; (2) the mechanisms of complement evasion by trypanosomes; and (3) host genetic deficiencies of complement lectin pathway factors that contribute to infection susceptibility and disease progression. This review will focus on trypanosomatids, the parasites that cause Chagas disease, leishmaniasis and sleeping sickness (African trypanosomiasis). |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 33% |
| United States | 1 | 33% |
| Kenya | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Philippines | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 99 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 19% |
| Researcher | 16 | 16% |
| Student > Master | 15 | 15% |
| Student > Bachelor | 14 | 14% |
| Student > Doctoral Student | 8 | 8% |
| Other | 16 | 16% |
| Unknown | 13 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 32% |
| Biochemistry, Genetics and Molecular Biology | 16 | 16% |
| Medicine and Dentistry | 13 | 13% |
| Immunology and Microbiology | 10 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Other | 10 | 10% |
| Unknown | 16 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2012.
All research outputs
#15,516,483
of 25,371,288 outputs
Outputs from Molecular Immunology
#2,686
of 3,884 outputs
Outputs of similar age
#113,191
of 191,581 outputs
Outputs of similar age from Molecular Immunology
#13
of 23 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,884 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 191,581 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.