| Title |
Mild Method for Preparation of 4,4‐Dimethyloxazoline Derivatives of Polyunsaturated Fatty Acids for GC–MS
|
|---|---|
| Published in |
Lipids, April 2011
|
| DOI | 10.1007/s11745-011-3550-4 |
| Pubmed ID | |
| Authors |
Vasily I. Svetashev |
| Abstract |
A mild and convenient method has been developed for preparing 4,4-dimethyloxazoline (DMOX) derivatives of fatty acids for GC-MS analysis. First, fatty acid methyl esters are converted to corresponding amides by incubation overnight at room temperature with 2-amino-2-methyl-1-propanol and a catalytic amount of sodium methoxide. The resulting 2-(methylpropanol) amides were isolated by partition between hexane-diethyl ether and water, and then converted to 4,4-dimethyloxazoline derivatives by treatment with trifluoroacetic anhydride under mild conditions (50 °C for 45 min). Structures of 2-methylpropanol amide and a DMOX derivative of oleic acid were confirmed by GC-MS. This method was applied to different FAME prepared from animal, plant or microbial lipids. The suggested method is most suitable for structure analysis of polyunsaturated fatty acids (PUFA) and for acids with double bonds in close to terminal positions. Application of the method is illustrated with spectra of the DMOX derivatives of 16:1(n-13), 24:5(n-6) and 24:6(n-3) acids. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 26% |
| Student > Ph. D. Student | 7 | 23% |
| Student > Master | 4 | 13% |
| Other | 2 | 6% |
| Lecturer | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 7 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 13 | 42% |
| Agricultural and Biological Sciences | 6 | 19% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Engineering | 1 | 3% |
| Unknown | 9 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 November 2011.
All research outputs
#18,317,537
of 22,681,577 outputs
Outputs from Lipids
#1,644
of 1,901 outputs
Outputs of similar age
#95,325
of 108,822 outputs
Outputs of similar age from Lipids
#7
of 7 outputs
Altmetric has tracked 22,681,577 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,901 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,822 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.