| Title |
Changes in olfactory bulb volume following lateralized olfactory training
|
|---|---|
| Published in |
Brain Imaging and Behavior, July 2016
|
| DOI | 10.1007/s11682-016-9567-9 |
| Pubmed ID | |
| Authors |
S. Negoias, K. Pietsch, T. Hummel |
| Abstract |
Repeated exposure to odors modifies olfactory function. Consequently, "olfactory training" plays a significant role in hyposmia treatment. In addition, numerous studies show that the olfactory bulb (OB) volume changes in disorders associated with olfactory dysfunction. Aim of this study was to investigate whether and how olfactory bulb volume changes in relation to lateralized olfactory training in healthy people. Over a period of 4 months, 97 healthy participants (63 females and 34 males, mean age: 23.74 ± 4.16 years, age range: 19-43 years) performed olfactory training by exposing the same nostril twice a day to 4 odors (lemon, rose, eucalyptus and cloves) while closing the other nostril. Before and after olfactory training, magnetic resonance imaging (MRI) scans were performed to measure OB volume. Furthermore, participants underwent lateralized odor threshold and odor identification testing using the "Sniffin' Sticks" test battery.OB volume increased significantly after olfactory training (11.3 % and 13.1 % respectively) for both trained and untrained nostril. No significant effects of sex, duration and frequency of training or age of the subjects were seen. Interestingly, PEA odor thresholds worsened after training, while olfactory identification remained unchanged.These data show for the first time in humans that olfactory training may involve top-down process, which ultimately lead to a bilateral increase in olfactory bulb volume. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 20% |
| United Kingdom | 1 | 20% |
| Netherlands | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 91 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 15% |
| Student > Ph. D. Student | 11 | 12% |
| Student > Doctoral Student | 11 | 12% |
| Student > Bachelor | 8 | 9% |
| Other | 5 | 5% |
| Other | 18 | 19% |
| Unknown | 26 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 28% |
| Psychology | 8 | 9% |
| Neuroscience | 8 | 9% |
| Agricultural and Biological Sciences | 7 | 8% |
| Social Sciences | 1 | 1% |
| Other | 4 | 4% |
| Unknown | 39 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2022.
All research outputs
#13,038,847
of 23,504,694 outputs
Outputs from Brain Imaging and Behavior
#431
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Outputs of similar age
#186,165
of 366,408 outputs
Outputs of similar age from Brain Imaging and Behavior
#9
of 24 outputs
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