| Title |
Epidemiology of basal-like breast cancer
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, June 2007
|
| DOI | 10.1007/s10549-007-9632-6 |
| Pubmed ID | |
| Authors |
Robert C. Millikan, Beth Newman, Chiu-Kit Tse, Patricia G. Moorman, Kathleen Conway, Lisa V. Smith, Miriam H. Labbok, Joseph Geradts, Jeannette T. Bensen, Susan Jackson, Sarah Nyante, Chad Livasy, Lisa Carey, H. Shelton Earp, Charles M. Perou |
| Abstract |
Risk factors for the newly identified "intrinsic" breast cancer subtypes (luminal A, luminal B, basal-like and human epidermal growth factor receptor 2-positive/estrogen receptor-negative) were determined in the Carolina Breast Cancer Study, a population-based, case-control study of African-American and white women. Immunohistochemical markers were used to subtype 1,424 cases of invasive and in situ breast cancer, and case subtypes were compared to 2,022 controls. Luminal A, the most common subtype, exhibited risk factors typically reported for breast cancer in previous studies, including inverse associations for increased parity and younger age at first full-term pregnancy. Basal-like cases exhibited several associations that were opposite to those observed for luminal A, including increased risk for parity and younger age at first term full-term pregnancy. Longer duration breastfeeding, increasing number of children breastfed, and increasing number of months breastfeeding per child were each associated with reduced risk of basal-like breast cancer, but not luminal A. Women with multiple live births who did not breastfeed and women who used medications to suppress lactation were at increased risk of basal-like, but not luminal A, breast cancer. Elevated waist-hip ratio was associated with increased risk of luminal A in postmenopausal women, and increased risk of basal-like breast cancer in pre- and postmenopausal women. The prevalence of basal-like breast cancer was highest among premenopausal African-American women, who also showed the highest prevalence of basal-like risk factors. Among younger African-American women, we estimate that up to 68% of basal-like breast cancer could be prevented by promoting breastfeeding and reducing abdominal adiposity. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 30% |
| Netherlands | 1 | 10% |
| Unknown | 6 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 90% |
| Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 423 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 2% |
| Japan | 2 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| France | 1 | <1% |
| Nigeria | 1 | <1% |
| Colombia | 1 | <1% |
| Mexico | 1 | <1% |
| Serbia | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 406 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 64 | 15% |
| Researcher | 57 | 13% |
| Student > Bachelor | 43 | 10% |
| Student > Master | 42 | 10% |
| Student > Doctoral Student | 33 | 8% |
| Other | 86 | 20% |
| Unknown | 98 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 137 | 32% |
| Agricultural and Biological Sciences | 62 | 15% |
| Biochemistry, Genetics and Molecular Biology | 47 | 11% |
| Nursing and Health Professions | 14 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 2% |
| Other | 42 | 10% |
| Unknown | 111 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2022.
All research outputs
#3,383,846
of 25,391,066 outputs
Outputs from Breast Cancer Research and Treatment
#508
of 4,981 outputs
Outputs of similar age
#8,231
of 78,741 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#7
of 41 outputs
Altmetric has tracked 25,391,066 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,981 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 78,741 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.