You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Optical control of antibacterial activity
|
|---|---|
| Published in |
Nature Chemistry, September 2013
|
| DOI | 10.1038/nchem.1750 |
| Pubmed ID | |
| Authors |
Willem A. Velema, Jan Pieter van der Berg, Mickel J. Hansen, Wiktor Szymanski, Arnold J. M. Driessen, Ben L. Feringa |
| Abstract |
Bacterial resistance is a major problem in the modern world, stemming in part from the build-up of antibiotics in the environment. Novel molecular approaches that enable an externally triggered increase in antibiotic activity with high spatiotemporal resolution and auto-inactivation are highly desirable. Here we report a responsive, broad-spectrum, antibacterial agent that can be temporally activated with light, whereupon it auto-inactivates on the scale of hours. The use of such a 'smart' antibiotic might prevent the build-up of active antimicrobial material in the environment. Reversible optical control over active drug concentration enables us to obtain pharmacodynamic information. Precisely localized control of activity is achieved, allowing the growth of bacteria to be confined to defined patterns, which has potential for the development of treatments that avoid interference with the endogenous microbial population in other parts of the organism. |
X Demographics
The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 32% |
| Netherlands | 3 | 11% |
| United Kingdom | 2 | 7% |
| Japan | 1 | 4% |
| Argentina | 1 | 4% |
| Oman | 1 | 4% |
| Indonesia | 1 | 4% |
| Ireland | 1 | 4% |
| Unknown | 9 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 54% |
| Scientists | 10 | 36% |
| Science communicators (journalists, bloggers, editors) | 3 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 384 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | <1% |
| United States | 3 | <1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| India | 1 | <1% |
| Spain | 1 | <1% |
| Iceland | 1 | <1% |
| Unknown | 373 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 105 | 27% |
| Student > Master | 48 | 13% |
| Researcher | 47 | 12% |
| Student > Bachelor | 45 | 12% |
| Student > Doctoral Student | 19 | 5% |
| Other | 46 | 12% |
| Unknown | 74 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 190 | 49% |
| Agricultural and Biological Sciences | 33 | 9% |
| Biochemistry, Genetics and Molecular Biology | 19 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 3% |
| Materials Science | 11 | 3% |
| Other | 36 | 9% |
| Unknown | 83 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 117. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2023.
All research outputs
#363,169
of 25,837,817 outputs
Outputs from Nature Chemistry
#203
of 3,379 outputs
Outputs of similar age
#2,688
of 213,710 outputs
Outputs of similar age from Nature Chemistry
#2
of 46 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,379 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 36.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,710 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.