You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Electric Fields Due to Synaptic Currents Sharpen Excitatory Transmission
|
|---|---|
| Published in |
Science, March 2008
|
| DOI | 10.1126/science.1154330 |
| Pubmed ID | |
| Authors |
Sergiy Sylantyev, Leonid P. Savtchenko, Yin-Ping Niu, Anton I. Ivanov, Thomas P. Jensen, Dimitri M. Kullmann, Min-Yi Xiao, Dmitri A. Rusakov |
| Abstract |
The synaptic response waveform, which determines signal integration properties in the brain, depends on the spatiotemporal profile of neurotransmitter in the synaptic cleft. Here, we show that electrophoretic interactions between AMPA receptor-mediated excitatory currents and negatively charged glutamate molecules accelerate the clearance of glutamate from the synaptic cleft, speeding up synaptic responses. This phenomenon is reversed upon depolarization and diminished when intracleft electric fields are weakened through a decrease in the AMPA receptor density. In contrast, the kinetics of receptor-mediated currents evoked by direct application of glutamate are voltage-independent, as are synaptic currents mediated by the electrically neutral neurotransmitter GABA. Voltage-dependent temporal tuning of excitatory synaptic responses may thus contribute to signal integration in neural circuits. |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 3% |
| Germany | 3 | 3% |
| France | 3 | 3% |
| Japan | 2 | 2% |
| United Kingdom | 2 | 2% |
| Hungary | 1 | <1% |
| Australia | 1 | <1% |
| Belarus | 1 | <1% |
| Unknown | 102 | 86% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 29% |
| Student > Ph. D. Student | 20 | 17% |
| Professor | 13 | 11% |
| Professor > Associate Professor | 12 | 10% |
| Student > Master | 10 | 8% |
| Other | 18 | 15% |
| Unknown | 11 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 52 | 44% |
| Neuroscience | 24 | 20% |
| Engineering | 5 | 4% |
| Psychology | 4 | 3% |
| Chemistry | 4 | 3% |
| Other | 16 | 13% |
| Unknown | 14 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2014.
All research outputs
#15,243,549
of 22,665,794 outputs
Outputs from Science
#67,072
of 77,822 outputs
Outputs of similar age
#68,658
of 80,941 outputs
Outputs of similar age from Science
#317
of 341 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 77,822 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 61.9. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,941 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 341 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.