| Title |
Long‐term treatment with methylphenidate for fatigue after traumatic brain injury
|
|---|---|
| Published in |
Acta Neurologica Scandinavica, March 2016
|
| DOI | 10.1111/ane.12587 |
| Pubmed ID | |
| Authors |
B. Johansson, A.‐P. Wentzel, P. Andréll, L. Rönnbäck, C. Mannheimer |
| Abstract |
Traumatic brain injury (TBI) may cause long-lasting post-concussive symptoms, such as mental fatigue and concentration difficulties, and this may become the main hindrance for returning to work and studies. There is currently no effective treatment for long-lasting mental fatigue. In this hypothesis generating study, the long-term effects of methylphenidate on mental fatigue, cognitive function, and safety were assessed. Thirty participants who suffered from long-term post-concussion symptoms after a mild TBI or moderate TBI and who had reported positive effects with methylphenidate during an initial phase of this follow-up study were treated with methylphenidate for a further six months. After six-month follow-up, effects on Mental Fatigue Scale (MFS), depression, anxiety, and cognitive function (processing speed, attention, working memory) were significantly improved compared to baseline data (P < 0.001, respectively). Heart rate was significantly increased (P = 0.01), while blood pressure was not changed. Individuals suffering from prolonged symptoms after TBI reported reduced mental fatigue and improved cognitive functions with long-term methylphenidate treatment. It is suggested that methylphenidate can be a treatment option for long-term mental fatigue and cognitive impairment after a TBI, but further randomized control research is warranted. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 25% |
| United Kingdom | 2 | 17% |
| Finland | 1 | 8% |
| Canada | 1 | 8% |
| Unknown | 5 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Unknown | 141 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 15% |
| Student > Bachelor | 19 | 13% |
| Student > Doctoral Student | 12 | 8% |
| Researcher | 11 | 8% |
| Other | 10 | 7% |
| Other | 25 | 17% |
| Unknown | 45 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 21% |
| Psychology | 26 | 18% |
| Neuroscience | 13 | 9% |
| Nursing and Health Professions | 6 | 4% |
| Sports and Recreations | 5 | 3% |
| Other | 11 | 8% |
| Unknown | 52 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2022.
All research outputs
#5,123,445
of 25,374,917 outputs
Outputs from Acta Neurologica Scandinavica
#609
of 2,168 outputs
Outputs of similar age
#74,735
of 314,268 outputs
Outputs of similar age from Acta Neurologica Scandinavica
#21
of 32 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,168 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,268 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.