↓ Skip to main content

Delta-9-Tetrahydrocannabinol (∆9-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats

Overview of attention for article published in Neurotoxicity Research, September 2017
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#3 of 933)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
3 news outlets
blogs
1 blog
twitter
81 X users
facebook
9 Facebook pages
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
110 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Delta-9-Tetrahydrocannabinol (∆9-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats
Published in
Neurotoxicity Research, September 2017
DOI 10.1007/s12640-017-9806-x
Pubmed ID
Authors

Noor Azuin Suliman, Che Norma Mat Taib, Mohamad Aris Mohd Moklas, Rusliza Basir

Abstract

Neurogenesis is influenced by various external factors such as enriched environments. Some researchers had postulated that neurogenesis has contributed to the hippocampal learning and memory. This project was designed to observe the effect of Delta-9-tetrahydrocannabinol (∆(9)-THC) in cognitive performance that influenced by the neurogenesis. Different doses of ∆(9)-THC were used for observing the neurogenesis mechanism occurs in the hippocampus of rats. The brains were stained with antibodies, namely BrdU, glial fibrillary acidic protein (GFAP), nestin, doublecortin (DCX) and class III β-tubulin (TuJ-1). The cognitive test was used novel-object discrimination test (NOD) while the proteins involved, DCX and brain-derived neurotrophic factor (BDNF), were measured. Throughout this study, ∆(9)-THC enhanced the markers involved in all stages of neurogenesis mechanism. Simultaneously, the cognitive behaviour of rat also showed improvement in learning and memory functions observed in behavioural test and molecular perspective. Administration of ∆(9)-THC was observed to enhance the neurogenesis in the brain, especially in hippocampus thus improved the cognitive function of rats.

X Demographics

X Demographics

The data shown below were collected from the profiles of 81 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 110 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 22 20%
Student > Ph. D. Student 16 15%
Researcher 14 13%
Student > Master 11 10%
Other 8 7%
Other 11 10%
Unknown 28 25%
Readers by discipline Count As %
Neuroscience 23 21%
Medicine and Dentistry 15 14%
Agricultural and Biological Sciences 10 9%
Pharmacology, Toxicology and Pharmaceutical Science 8 7%
Biochemistry, Genetics and Molecular Biology 8 7%
Other 11 10%
Unknown 35 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 102. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2024.
All research outputs
#424,226
of 25,822,778 outputs
Outputs from Neurotoxicity Research
#3
of 933 outputs
Outputs of similar age
#8,703
of 326,921 outputs
Outputs of similar age from Neurotoxicity Research
#2
of 30 outputs
Altmetric has tracked 25,822,778 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 933 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,921 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.