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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Growth Inhibitory Potential and Antimetastatic Effect of Camel Urine on Breast Cancer Cells In Vitro and In Vivo
|
|---|---|
| Published in |
Integrative Cancer Therapies, June 2016
|
| DOI | 10.1177/1534735416656051 |
| Pubmed ID | |
| Authors |
Firdaus Romli, Nadiah Abu, Faten A. Khorshid, Syed Umar Faruq Syed Najmuddin, Yeap Swee Keong, Nurul Elyani Mohamad, Muhajir Hamid, Noorjahan Banu Alitheen, Nik Mohd Afizan Nik Abd Rahman |
| Abstract |
Although it may sound unpleasant, camel urine has been consumed extensively for years in the Middle East as it is believed to be able to treat a wide range of diseases such as fever, cold, or even cancer. People usually take it by mixing small drops with camel milk or take it directly. The project aims to study the effects of camel urine in inhibiting the growth potential and metastatic ability of 4T1 cancer cell line in vitro and in vivo. Based on the MTT result, the cytotoxicity of camel urine against 4T1 cell was established, and it was dose-dependent. Additionally, the antimetastatic potential of camel urine was tested by running several assays such as scratch assay, migration and invasion assay, and mouse aortic ring assay with promising results in the ability of camel urine to inhibit metastatic process of the 4T1 cells. In order to fully establish camel urine's potential, an in vivo study was carried out by treating mice inoculated with 4T1 cells with 2 different doses of camel urine. By the end of the treatment period, the tumor in both treated groups had reduced in size as compared to the control group. Additional assays such as the TUNEL assay, immunophenotyping, cytokine level detection assay, clonogenic assay, and proteome profiler demonstrated the capability of camel urine to reduce and inhibit the metastatic potential of 4T1 cells in vivo. To sum up, further study of anticancer properties of camel urine is justified, as evidenced through the in vitro and in vivo studies carried out. Better results were obtained at higher concentration of camel urine used in vivo. Apart from that, this project has laid out the mechanisms employed by the substance to inhibit the growth and the metastatic process of the 4T1 cell. |
X Demographics
The data shown below were collected from the profiles of 87 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Saudi Arabia | 5 | 6% |
| Indonesia | 4 | 5% |
| Malaysia | 4 | 5% |
| United Kingdom | 3 | 3% |
| India | 2 | 2% |
| United States | 2 | 2% |
| Algeria | 2 | 2% |
| Pakistan | 2 | 2% |
| Japan | 1 | 1% |
| Other | 7 | 8% |
| Unknown | 55 | 63% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 80 | 92% |
| Scientists | 5 | 6% |
| Practitioners (doctors, other healthcare professionals) | 1 | 1% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 5 | 11% |
| Student > Master | 4 | 9% |
| Researcher | 3 | 7% |
| Lecturer | 3 | 7% |
| Student > Bachelor | 3 | 7% |
| Other | 12 | 27% |
| Unknown | 15 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 20% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Unspecified | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Nursing and Health Professions | 2 | 4% |
| Other | 7 | 16% |
| Unknown | 18 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 83. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2024.
All research outputs
#522,228
of 25,768,270 outputs
Outputs from Integrative Cancer Therapies
#20
of 859 outputs
Outputs of similar age
#10,316
of 369,925 outputs
Outputs of similar age from Integrative Cancer Therapies
#4
of 140 outputs
Altmetric has tracked 25,768,270 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 859 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,925 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.