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Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells

Overview of attention for article published in BMC Complementary Medicine and Therapies, December 2014
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Title
Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells
Published in
BMC Complementary Medicine and Therapies, December 2014
DOI 10.1186/1472-6882-14-469
Pubmed ID
Authors

Su-Wen Lim, Hwei-San Loh, Kang-Nee Ting, Tracey D Bradshaw, Nazariah A Zeenathul

Abstract

Tocotrienols, especially the gamma isomer was discovered to possess cytotoxic effects associated with the induction of apoptosis in numerous cancers. Individual tocotrienol isomers are believed to induce dissimilar apoptotic mechanisms in different cancer types. This study was aimed to compare the cytotoxic potency of alpha-, gamma- and delta-tocotrienols, and to explore their resultant apoptotic mechanisms in human lung adenocarcinoma A549 and glioblastoma U87MG cells which are scarcely researched.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 19%
Student > Ph. D. Student 11 17%
Student > Master 10 16%
Student > Doctoral Student 4 6%
Researcher 4 6%
Other 10 16%
Unknown 13 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 22%
Biochemistry, Genetics and Molecular Biology 13 20%
Medicine and Dentistry 13 20%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Chemistry 3 5%
Other 5 8%
Unknown 12 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2016.
All research outputs
#18,385,510
of 22,772,779 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,504
of 3,623 outputs
Outputs of similar age
#260,623
of 359,669 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#62
of 89 outputs
Altmetric has tracked 22,772,779 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,623 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,669 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 89 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.