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Mendeley readers
Attention Score in Context
| Title |
Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
|
|---|---|
| Published in |
Cancer Cell International, June 2009
|
| DOI | 10.1186/1475-2867-9-16 |
| Pubmed ID | |
| Authors |
Yusmazura Zakaria, Asmah Rahmat, Azimahtol Hawariah Lope Pihie, Noor Rain Abdullah, Peter J Houghton |
| Abstract |
Eurycomanone is a cytotoxic compound found in Eurycoma longifolia Jack. Previous studies had noted the cytotoxic effect against various cancer cell lines. The aim of this study is to investigate the cytotoxicity against human hepato carcinoma cell in vitro and the mode of action. The cytotoxicity of eurycomanone was evaluated using MTT assay and the mode of cell death was detected by Hoechst 33258 nuclear staining and flow cytometry with Annexin-V/propidium iodide double staining. The protein expression Bax, Bcl-2, p53 and cytochrome C were studied by flow cytometry using a spesific antibody conjugated fluorescent dye to confirm the up-regulation of p53 and Bax in cancer cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 3 | 3% |
| Malaysia | 1 | 1% |
| Unknown | 82 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 30% |
| Researcher | 13 | 15% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 8 | 9% |
| Student > Postgraduate | 6 | 7% |
| Other | 11 | 13% |
| Unknown | 11 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 31 | 36% |
| Biochemistry, Genetics and Molecular Biology | 9 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
| Chemistry | 6 | 7% |
| Medicine and Dentistry | 6 | 7% |
| Other | 10 | 12% |
| Unknown | 17 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2012.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Cancer Cell International
#1,796
of 2,231 outputs
Outputs of similar age
#118,970
of 123,604 outputs
Outputs of similar age from Cancer Cell International
#4
of 4 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,231 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,604 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.