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The Prophylactic Effect of Probiotic Enterococcus lactis IW5 against Different Human Cancer Cells

Overview of attention for article published in Frontiers in Microbiology, November 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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6 X users
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1 patent

Citations

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91 Mendeley
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Title
The Prophylactic Effect of Probiotic Enterococcus lactis IW5 against Different Human Cancer Cells
Published in
Frontiers in Microbiology, November 2015
DOI 10.3389/fmicb.2015.01317
Pubmed ID
Authors

Yousef Nami, Babak Haghshenas, Minoo Haghshenas, Norhafizah Abdullah, Ahmad Yari Khosroushahi

Abstract

Enterococcus lactis IW5 was obtained from human gut and the potential probiotic characteristics of this organism were then evaluated. Results showed that this strain was highly resistant to low pH and high bile salt and adhered strongly to Caco-2 human epithelial colorectal cell lines. The supernatant of E. lactis IW5 strongly inhibited the growth of several pathogenic bacteria and decreased the viability of different cancer cells, such as HeLa, MCF-7, AGS, HT-29, and Caco-2. Conversely, E. lactis IW5 did not inhibit the viability of normal FHs-74 cells. This strain did not generate toxic enzymes, including β-glucosidase, β-glucuronidase, and N-acetyl-β-glucosaminidase and was highly susceptible to ampicillin, gentamycin, penicillin, vancomycin, clindamycin, sulfamethoxazol, and chloramphenicol but resistant to erythromycin and tetracyclin. This study provided evidence for the effect of E. lactis IW5 on cancer cells. Therefore, E. lactis IW5, as a bioactive therapeutics, should be subjected to other relevant tests to verify the therapeutic suitability of this strain for clinical applications.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 91 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 15%
Researcher 10 11%
Student > Master 10 11%
Student > Bachelor 8 9%
Student > Doctoral Student 5 5%
Other 12 13%
Unknown 32 35%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 24%
Biochemistry, Genetics and Molecular Biology 15 16%
Immunology and Microbiology 11 12%
Chemistry 4 4%
Unspecified 2 2%
Other 3 3%
Unknown 34 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2022.
All research outputs
#5,507,692
of 25,732,188 outputs
Outputs from Frontiers in Microbiology
#5,400
of 29,747 outputs
Outputs of similar age
#82,587
of 395,566 outputs
Outputs of similar age from Frontiers in Microbiology
#77
of 422 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 29,747 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,566 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 422 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.