↓ Skip to main content

Statin Use and the Risk of Kidney Disease With Long-Term Follow-Up (8.4-Year Study)

Overview of attention for article published in American Journal of Cardiology, December 2015
Altmetric Badge
27

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
twitter
25 X users
facebook
7 Facebook pages

Citations

dimensions_citation
33 Dimensions

Readers on

mendeley
63 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Statin Use and the Risk of Kidney Disease With Long-Term Follow-Up (8.4-Year Study)
Published in
American Journal of Cardiology, December 2015
DOI 10.1016/j.amjcard.2015.11.031
Pubmed ID
Authors

Tushar Acharya, Jian Huang, Steven Tringali, Christopher R. Frei, Eric M. Mortensen, Ishak A. Mansi

Abstract

Few studies have examined long-term effects of statin therapy on kidney diseases. The objective of this study was to determine the association of statin use with incidence of acute and chronic kidney diseases after prolonged follow-up. In this retrospective cohort study, we analyzed data from the San Antonio area military health care system from October 2003 through March 2012. Statin users were propensity score matched to nonusers using 82 baseline characteristics including demographics, co-morbidities, medications, and health care utilization. Study outcomes were acute kidney injury, chronic kidney disease (CKD), and nephritis/nephrosis/renal sclerosis. Of the 43,438 subjects included, we propensity score matched 6,342 statin users with 6,342 nonusers. Statin users had greater odds of acute kidney injury (odds ratio [OR] 1.30, 95% confidence interval [CI] 1.14 to 1.48), CKD (OR 1.36, 95% CI 1.22 to 1.52), and nephritis/nephrosis/renal sclerosis (OR 1.35, 95% CI 1.05 to 1.73). In a subset of patients without co-morbidities, the association of statin use with CKD remained significant (OR 1.53, 95% CI 1.27 to 1.85). In a secondary analysis, adjusting for diseases/conditions that developed during follow-up weakened this association. In conclusion, statin use is associated with increased incidence of acute and chronic kidney disease. These findings are cautionary and suggest that long-term effects of statins in real-life patients may differ from shorter term effects in selected clinical trial populations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
Unknown 62 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 19%
Student > Bachelor 10 16%
Professor 5 8%
Other 5 8%
Student > Postgraduate 5 8%
Other 13 21%
Unknown 13 21%
Readers by discipline Count As %
Medicine and Dentistry 24 38%
Biochemistry, Genetics and Molecular Biology 5 8%
Nursing and Health Professions 5 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 8%
Social Sciences 3 5%
Other 4 6%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2024.
All research outputs
#1,434,333
of 25,371,288 outputs
Outputs from American Journal of Cardiology
#332
of 10,180 outputs
Outputs of similar age
#23,714
of 395,281 outputs
Outputs of similar age from American Journal of Cardiology
#12
of 118 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,180 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,281 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.