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Topical negative pressure for treating chronic wounds

Overview of attention for article published in Cochrane database of systematic reviews, July 2008
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Title
Topical negative pressure for treating chronic wounds
Published in
Cochrane database of systematic reviews, July 2008
DOI 10.1002/14651858.cd001898.pub2
Pubmed ID
Authors

Ubbink, Dirk T, Westerbos, Stijn Joël, Evans, Debra, Land, Lucy, Vermeulen, Hester

Abstract

Chronic wounds mainly affect the elderly and those with multiple health problems. Despite the use of modern dressings, some of these wounds take a long time to heal, fail to heal, or recur, causing significant pain and discomfort to the person and cost to health services. Topical negative pressure (TNP) is used to promote healing of surgical wounds by using suction to drain excess fluid from wounds. To assess the effects of TNP on chronic wound healing. For this second update of this review we searched the Cochrane Wounds Group Specialised Register (December 2007), The Cochrane Central Register of Controlled Trials (CENTRAL) - The Cochrane Library Issue 4, 2007, Ovid MEDLINE - 1950 to November Week 2 2007, Ovid EMBASE - 1982 to 2007 Week 50 and Ovid CINAHL - 1980 to December Week 1 2007. In addition, we contacted authors, companies, manufacturers, and distributors to identify relevant trials and information. All randomised controlled trials which evaluated the effects of TNP on people with chronic wounds. Selection of the trials, quality assessment, data abstraction, and data synthesis were done by two authors independently. Disagreements were solved by discussion. Two trials were included in the original review. A further five trials were included in this second update resulting in a total of seven trials involving 205 participants. The seven trials compared TNP with five different comparator treatments. Four trials compared TNP with gauze soaked in either 0.9% saline or Ringer's solution. The other three trials compared TNP with hydrocolloid gel plus gauze, a treatment package comprising papain-urea topical treatment, and cadexomer iodine or hydrocolloid, hydrogels, alginate and foam. These data do not show that TNP significantly increases the healing rate of chronic wounds compared with comparators. Data on secondary outcomes such as infection rate, quality of life, oedema, hospitalisation and bacterial load were not reported. Trials comparing TNP with alternative treatments for chronic wounds have methodological flaws and data do demonstrate a beneficial effect of TNP on wound healing however more, better quality research is needed.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 2%
Unknown 135 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 10%
Student > Master 14 10%
Student > Bachelor 14 10%
Student > Ph. D. Student 10 7%
Other 10 7%
Other 28 20%
Unknown 48 35%
Readers by discipline Count As %
Medicine and Dentistry 56 41%
Nursing and Health Professions 12 9%
Agricultural and Biological Sciences 8 6%
Engineering 7 5%
Physics and Astronomy 1 <1%
Other 2 1%
Unknown 52 38%