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Dietary advice in pregnancy for preventing gestational diabetes mellitus

Overview of attention for article published in this source, April 2008
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Title
Dietary advice in pregnancy for preventing gestational diabetes mellitus
Published by
John Wiley & Sons, Ltd, April 2008
DOI 10.1002/14651858.cd006674.pub2
Pubmed ID
Authors

Tieu, Joanna, Crowther, Caroline A, Middleton, Philippa

Abstract

Gestational diabetes mellitus (GDM) is a form of diabetes that occurs during pregnancy which can result in significant adverse outcomes for mother and child both in the short and long term. The potential for adverse outcomes, in addition to the increasing prevalence of gestational diabetes worldwide, demonstrates the need to assess strategies, such as dietary advice, that might prevent gestational diabetes. To assess the effects of dietary advice in preventing gestational diabetes mellitus. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (January 2008) and reference lists of retrieved articles. Quasi-randomised and randomised studies of dietary intervention for preventing glucose intolerance in pregnancy. Two review authors independently conducted data extraction and quality assessment. We resolved disagreements through discussion or through a third author. Three trials (107 women) were included in the review. One trial (25 pregnant women) analysed high-fibre diets with no included outcomes showing statistically significant differences. Two trials (82 pregnant women) assessed low glycaemic index (LGI) versus high glycaemic index diets for pregnant women. Women on the LGI diet had fewer large for gestational age infants (one trial; relative risk (RR) 0.09, 95% confidence interval (CI) 0.01 to 0.69), infants with lower ponderal indexes (two trials; weighted mean difference (WMD) -0.18, 95% CI -0.32 to -0.04, random-effects analysis) and lower maternal fasting glucose levels (two trials; WMD -0.28 mmol/L 95% CI -0.54 to -0.02, random-effects model). Results for women on the LGI diet on neonatal birth weight were not conclusive under a random-effects model (two trials; WMD -527.64 g, 95% CI -1119.20 to 63.92); however, on a fixed-effect model, women on the LGI diet gave birth to lighter babies (two trials; WMD -445.55 g, 95% CI -634.16 to -256.95). High heterogeneity was observed between the trials in most results and both were relatively small trials. One of these trials also included a standard exercise regimen for all participants. While a low glycaemic index diet was seen to be beneficial for some outcomes for both mother and child, results from the review were inconclusive. Further trials with large sample sizes and longer follow up are required to make more definitive conclusions. No conclusions could be drawn from the high-fibre versus control-diet comparison since the trial involved did not report on many of the outcomes we prespecified.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 210 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ireland 1 <1%
Tanzania, United Republic of 1 <1%
Australia 1 <1%
Unknown 207 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 43 20%
Student > Ph. D. Student 30 14%
Student > Bachelor 29 14%
Researcher 25 12%
Student > Postgraduate 15 7%
Other 37 18%
Unknown 31 15%
Readers by discipline Count As %
Medicine and Dentistry 84 40%
Nursing and Health Professions 29 14%
Social Sciences 15 7%
Agricultural and Biological Sciences 15 7%
Biochemistry, Genetics and Molecular Biology 5 2%
Other 20 10%
Unknown 42 20%