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Chinese herbal medicine for subfertile women with polycystic ovarian syndrome

Overview of attention for article published in Cochrane database of systematic reviews, September 2010
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Title
Chinese herbal medicine for subfertile women with polycystic ovarian syndrome
Published in
Cochrane database of systematic reviews, September 2010
DOI 10.1002/14651858.cd007535.pub2
Pubmed ID
Authors

Zhang J, Li T, Zhou L, Tang L, Xu L, Wu T, Lim DC, Zhang, Jing, Li, Tingting, Zhou, Lingling, Tang, Liulin, Xu, Liangzhi, Wu, Taixiang, Lim, Danforn Ce

Abstract

Polycystic ovarian syndrome (PCOS) is one of the most common reproductive endocrinology abnormalities, affecting 5% to 10% of women of reproductive age. Western medicines, such as oral contraceptives and insulin sensitizers, have been widely used to improve the symptoms and signs for PCOS. Recently, many studies have been published considering Chinese herbal medicine (CHM) as an alternative treatment for women with PCOS. To evaluate the efficacy and safety of Chinese medicinal herbs for subfertile women with PCOS. We searched the following databases (from inception to March 2010): Menstrual Disorders and Subfertility Group Specialised Register (MDSG), Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Allied and Complementary Medicine (AMED), PsycINFO, Chinese National Knowledge Infrastructure (CNKI), VIP, Wanfang. In addition, all reference lists of included trials were searched and experts in the field were contacted to locate trials. Randomized controlled trials (RCT) considering the use of CHM for the treatment of subfertile women with PCOS. Two review authors independently screened appropriate trials for inclusion, assessed methodological quality, and extracted data. We contacted primary authors for additional information. Meta-analysis was conducted. Odds ratio (OR) was used for reporting dichotomous data with 95% confidence intervals (CI). Four RCTs involving 344 participants were included. The methodological risk of bias of included studies was poor. Different interventions were used in these four RCTs.There was evidence of statistically significant difference seen improving pregnancy rate (per woman) between CHM plus clomiphene and clomiphene (OR 2.97, 95%CI 1.71 to 5.17). However, there was no statistically significant difference seen in the other comparison groups for improving pregnancy rate (per woman).There was no evidence of statistically significant difference in improving ovulation rate (per woman) between CHM and clomiphene (OR 1.42, 95%CI 0.19 to 10.49), between CHM plus laparoscopic ovarian drilling (LOD) and LOD (OR 2.43, 95%CI 0.39 to 15.08).There were not statistically significant difference between CHM plus follicle aspiration, ovulation induction and follicle aspiration plus ovulation induction for adverse events including LUFS, OHSS and multiple pregnancy.Live birth rate was not reported by any studies. There is limited evidence that the addition of CHM to clomiphene is associated with improved clinical pregnancy outcomes and no other evidence of any other effect. The methodology of RCTs was not adequately reported by primary studies.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 2%
United States 1 2%
Unknown 53 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 24%
Student > Ph. D. Student 9 16%
Student > Doctoral Student 5 9%
Librarian 4 7%
Student > Bachelor 4 7%
Other 14 25%
Unknown 6 11%
Readers by discipline Count As %
Medicine and Dentistry 29 53%
Nursing and Health Professions 6 11%
Agricultural and Biological Sciences 5 9%
Biochemistry, Genetics and Molecular Biology 4 7%
Immunology and Microbiology 2 4%
Other 3 5%
Unknown 6 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2015.
All research outputs
#18,405,972
of 22,799,071 outputs
Outputs from Cochrane database of systematic reviews
#11,427
of 12,312 outputs
Outputs of similar age
#85,408
of 95,254 outputs
Outputs of similar age from Cochrane database of systematic reviews
#74
of 79 outputs
Altmetric has tracked 22,799,071 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,312 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.4. This one is in the 2nd percentile – i.e., 2% of its peers scored the same or lower than it.
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We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.