Title |
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease.
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Published in |
Cochrane database of systematic reviews, October 2011
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DOI | 10.1002/14651858.cd007751.pub2 |
Pubmed ID | |
Authors |
Pawana Sharma, Rachel C Blackburn, Claire L Parke, Keith McCullough, Angharad Marks, Corri Black |
Abstract |
Chronic kidney disease (CKD) is a long term condition that occurs as a result of damage to the kidneys. Early recognition of CKD is becoming increasingly common due to widespread laboratory estimated glomerular filtration rate (eGFR) reporting, raised clinical awareness, and international adoption of Kidney Disease Outcomes Quality Initiative (K/DOQI) classification. Early recognition and management of CKD affords the opportunity not only to prepare for progressive kidney impairment and impending renal replacement therapy, but also for intervening to reduce the risk of progression and cardiovascular disease. Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) are two classes of antihypertensive drugs that act on the renin-angiotensin-aldosterone system. Beneficial effects of ACEi and ARB on renal outcomes and survival in people with a wide range of severity of renal impairment have been reported; however, their effectiveness in the subgroup of people with early CKD (stage 1 to 3) is less certain. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 7 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Austria | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 159 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 21 | 13% |
Researcher | 19 | 12% |
Student > Bachelor | 18 | 11% |
Student > Ph. D. Student | 15 | 9% |
Student > Postgraduate | 14 | 9% |
Other | 28 | 17% |
Unknown | 47 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 71 | 44% |
Nursing and Health Professions | 8 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 5% |
Agricultural and Biological Sciences | 3 | 2% |
Psychology | 3 | 2% |
Other | 16 | 10% |
Unknown | 53 | 33% |