Title |
Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion
|
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Published in |
Cochrane database of systematic reviews, January 2013
|
DOI | 10.1002/14651858.cd009510.pub2 |
Pubmed ID | |
Authors |
Danny Mitry, Catey Bunce, David Charteris |
Abstract |
Branch retinal vein occlusion (BRVO) is one of the most common occurring retinal vascular abnormalities. The pathogenesis of BRVO is thought to involve both retinal vein compression and damage to the vessel wall, possibly leading to thrombus formation at sites where retinal arterioles cross retinal veins. The most common cause of visual loss in patients with BRVO is macular oedema (MO). Grid or focal laser photocoagulation has been shown to reduce the risk of visual loss and improve visual acuity (VA) in up to two thirds of individuals with MO secondary to BRVO, however, limitations to this treatment exist and newer modalities have suggested equal or improved efficacy. Recently, antiangiogenic therapy with anti-vascular endothelial growth factor (anti-VEGF) has been used successfully to treat MO resulting from a variety of causes. As elevated intraocular levels of VEGF have been demonstrated in patients with retinal vein occlusions there is a strong basis for the hypothesis that anti-VEGF agents may be beneficial in the treatment of vascular leakage and MO. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 1% |
Austria | 1 | <1% |
France | 1 | <1% |
Brazil | 1 | <1% |
Australia | 1 | <1% |
Unknown | 141 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 25 | 17% |
Researcher | 19 | 13% |
Student > Ph. D. Student | 18 | 12% |
Student > Bachelor | 15 | 10% |
Student > Postgraduate | 11 | 7% |
Other | 28 | 19% |
Unknown | 31 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 60 | 41% |
Nursing and Health Professions | 12 | 8% |
Agricultural and Biological Sciences | 12 | 8% |
Biochemistry, Genetics and Molecular Biology | 4 | 3% |
Psychology | 4 | 3% |
Other | 18 | 12% |
Unknown | 37 | 25% |