Title |
Bronchoscopy-guided antimicrobial therapy for cystic fibrosis
|
---|---|
Published by |
John Wiley & Sons, Ltd, December 2013
|
DOI | 10.1002/14651858.cd009530.pub2 |
Pubmed ID | |
Authors |
Jain, Kamini, Wainwright, Claire, Smyth, Alan R |
Abstract |
Early diagnosis and treatment of lower respiratory tract infections, particularly those with Pseudomonas aeruginosa, are the mainstay of management of lung disease in cystic fibrosis. When sputum samples are unavailable, treatment relies mainly on cultures from oropharyngeal specimens; however, there are concerns regarding the sensitivity of these to identify lower respiratory organisms.Bronchoscopy and related procedures (including bronchoalveolar lavage) though invasive, allow the collection of lower respiratory specimens from non-sputum producers. Cultures of bronchoscopic specimens provide a higher yield of organisms compared to those from oropharyngeal specimens. Regular use of bronchoscopy and related procedures may help in a more accurate diagnosis of lower respiratory tract infections and guide the selection of antimicrobials, which may lead to clinical benefits. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 14% |
Mexico | 1 | 14% |
United Kingdom | 1 | 14% |
Unknown | 4 | 57% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 71% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 17% |
Student > Ph. D. Student | 5 | 12% |
Student > Bachelor | 5 | 12% |
Student > Postgraduate | 3 | 7% |
Student > Doctoral Student | 2 | 5% |
Other | 7 | 17% |
Unknown | 12 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 37% |
Nursing and Health Professions | 3 | 7% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Social Sciences | 2 | 5% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Other | 3 | 7% |
Unknown | 15 | 37% |