Title |
Retinoic acid post consolidation therapy for high‐risk neuroblastoma patients treated with autologous hematopoietic stem cell transplantation
|
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Published in |
Cochrane database of systematic reviews, January 2015
|
DOI | 10.1002/14651858.cd010685.pub2 |
Pubmed ID | |
Authors |
Frank Peinemann, Elvira C van Dalen, Doreen A Tushabe, Frank Berthold, Peinemann F; van Dalen EC; Tushabe DA; Berthold F, Peinemann F, van Dalen EC, Tushabe DA, Berthold F |
Abstract |
Neuroblastoma is a rare malignant disease and mainly affects infants and very young children. The tumors mainly develop in the adrenal medullary tissue and an abdominal mass is the most common presentation. About 50% of patients have metastatic disease at diagnosis. The high-risk group is characterized by metastasis and other characteristics that increase the risk for an adverse outcome. High-risk patients have a five-year event-free survival of less than 50%. Retinoic acid has been shown to inhibit growth of human neuroblastoma cells and has been considered as a potential candidate for improving the outcome of patients with high-risk neuroblastoma. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
Netherlands | 1 | 20% |
United States | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 55 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 22% |
Student > Master | 9 | 16% |
Student > Bachelor | 9 | 16% |
Researcher | 6 | 11% |
Other | 4 | 7% |
Other | 8 | 15% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 40% |
Biochemistry, Genetics and Molecular Biology | 6 | 11% |
Agricultural and Biological Sciences | 5 | 9% |
Immunology and Microbiology | 4 | 7% |
Nursing and Health Professions | 2 | 4% |
Other | 5 | 9% |
Unknown | 11 | 20% |