| Title |
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease
|
|---|---|
| Published in |
Cochrane database of systematic reviews, September 2016
|
| DOI | 10.1002/14651858.cd003733.pub4 |
| Pubmed ID | |
| Authors |
Jennifer M Knight‐Madden, Ian R Hambleton |
| Abstract |
Bronchodilators are used to treat bronchial hyper-responsiveness in asthma. Bronchial hyper-responsiveness may be a component of acute chest syndrome in people with sickle cell disease. Therefore, bronchodilators may be useful in the treatment of acute chest syndrome. This is an update of a previously published Cochrane Review. To assess the benefits and risks associated with the use of bronchodilators in people with acute chest syndrome. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register comprising references identified from comprehensive electronic database searches, handsearches of relevant journals and abstract books of conference proceedings. Additional searches were carried out on MEDLINE (1966 to 2002) and Embase (1981 to 2002).Date of the most recent search of the Group's Haemoglobinopathies Trials Register: 11 July 2016. Randomised or quasi-randomised controlled trials. Trials using quasi-randomisation methods will be included in future updates of this review if there is sufficient evidence that the treatment and control groups are similar at baseline. We found no trials investigating the use of bronchodilators for acute chest syndrome in people with sickle cell disease. We found no trials investigating the use of bronchodilators for acute chest syndrome in people with sickle cell disease. If bronchial hyper-responsiveness is an important component of some episodes of acute chest syndrome in people with sickle cell disease, the use of inhaled bronchodilators may be indicated. There is need for a well-designed, adequately-powered randomised controlled trial to assess the benefits and risks of the addition of inhaled bronchodilators to established therapies for acute chest syndrome in people with sickle cell disease. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 1% |
| Unknown | 85 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 9% |
| Researcher | 8 | 9% |
| Student > Bachelor | 8 | 9% |
| Student > Doctoral Student | 5 | 6% |
| Student > Ph. D. Student | 4 | 5% |
| Other | 10 | 12% |
| Unknown | 43 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 20% |
| Nursing and Health Professions | 14 | 16% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Social Sciences | 3 | 3% |
| Psychology | 1 | 1% |
| Other | 3 | 3% |
| Unknown | 45 | 52% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2016.
All research outputs
#20,723,696
of 25,457,858 outputs
Outputs from Cochrane database of systematic reviews
#10,914
of 11,499 outputs
Outputs of similar age
#256,487
of 331,047 outputs
Outputs of similar age from Cochrane database of systematic reviews
#226
of 238 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,499 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 40.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,047 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 238 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.