| Title |
Coenzyme Q10 for heart failure
|
|---|---|
| Published in |
Cochrane database of systematic reviews, June 2014
|
| DOI | 10.1002/14651858.cd008684.pub2 |
| Pubmed ID | |
| Authors |
Mohammed E Madmani, Ahmad Yusuf Solaiman, Khalil Tamr Agha, Yasser Madmani, Yasser Shahrour, Adib Essali, Waleed Kadro |
| Abstract |
Coenzyme Q10, or ubiquinone, is a non-prescription nutritional supplement. It is a fat-soluble molecule that acts as an electron carrier in mitochondria and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitude of diseases including heart failure. The severity of HF correlates with the severity of Coenzyme Q10 deficiency. Emerging data suggests that oxidative stress is increased in patients with HF and coenzyme Q10 may reduce oxidative stress because of its antioxidant activity. Coenzyme Q10 may also have a role in stabilizing myocardial calcium-dependent ion channels and preventing the consumption of metabolites essential for (ATP) synthesis. Coenzyme Q10, although is not a primary recommended treatment for heart failure, could be beneficial to patients with heart failure. Several randomized controlled trials, compared Coenzyme Q10 to other therapeutic modalities, have been conducted but no Cochrane-style review has been done. |
X Demographics
The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 27% |
| United States | 3 | 20% |
| Australia | 1 | 7% |
| Spain | 1 | 7% |
| Unknown | 6 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 80% |
| Scientists | 1 | 7% |
| Practitioners (doctors, other healthcare professionals) | 1 | 7% |
| Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 247 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| United States | 2 | <1% |
| Indonesia | 1 | <1% |
| Ireland | 1 | <1% |
| Unknown | 241 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 50 | 20% |
| Student > Bachelor | 31 | 13% |
| Researcher | 27 | 11% |
| Student > Ph. D. Student | 18 | 7% |
| Other | 17 | 7% |
| Other | 45 | 18% |
| Unknown | 59 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 76 | 31% |
| Nursing and Health Professions | 28 | 11% |
| Biochemistry, Genetics and Molecular Biology | 11 | 4% |
| Agricultural and Biological Sciences | 11 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 3% |
| Other | 42 | 17% |
| Unknown | 71 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2024.
All research outputs
#1,880,459
of 25,655,374 outputs
Outputs from Cochrane database of systematic reviews
#4,029
of 13,151 outputs
Outputs of similar age
#18,099
of 241,958 outputs
Outputs of similar age from Cochrane database of systematic reviews
#76
of 233 outputs
Altmetric has tracked 25,655,374 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,151 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.0. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 233 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.