Title |
Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO‐defined non‐severe pneumonia and wheeze
|
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Published in |
Cochrane database of systematic reviews, May 2014
|
DOI | 10.1002/14651858.cd009576.pub2 |
Pubmed ID | |
Authors |
Zohra S Lassi, Rohail Kumar, Jai K Das, Rehana A Salam, Zulfiqar A Bhutta |
Abstract |
Worldwide, pneumonia is the leading cause of death among children under five years of age and accounts for approximately two million deaths annually. The World Health Organization (WHO) has developed case management guidelines based on simple clinical signs to help clinicians decide on the appropriate pneumonia treatment. Children and infants who exhibit fast breathing (50 breaths per minute or more in infants two months to 12 months of age and 40 or more in children 12 months to five years of age) and cough are presumed to have non-severe pneumonia and the WHO recommends antibiotics. Implementation of these guidelines to identify and manage pneumonia at the community level has been shown to reduce acute respiratory infection (ARI)-related mortality by 36%, although apprehension exists regarding these results due to the questionable quality of evidence. As WHO guidelines do not make a distinction between viral and bacterial pneumonia, these children continue to receive antibiotics because of the concern that it may not be safe to do otherwise. Therefore, it is essential to explore the role of antibiotics in children with WHO-defined non-severe pneumonia and wheeze and to develop effective guidelines for initial antibiotic treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 5 | 38% |
Australia | 2 | 15% |
United Kingdom | 2 | 15% |
Malaysia | 1 | 8% |
Lithuania | 1 | 8% |
Unknown | 2 | 15% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 62% |
Practitioners (doctors, other healthcare professionals) | 3 | 23% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 137 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 22 | 16% |
Researcher | 20 | 15% |
Student > Bachelor | 19 | 14% |
Other | 15 | 11% |
Student > Postgraduate | 9 | 7% |
Other | 24 | 18% |
Unknown | 28 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 59 | 43% |
Nursing and Health Professions | 13 | 9% |
Social Sciences | 5 | 4% |
Immunology and Microbiology | 4 | 3% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Other | 18 | 13% |
Unknown | 35 | 26% |