Title |
Obesity Increases the Duration of Influenza A Virus Shedding in Adults
|
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Published in |
Journal of Infectious Diseases, August 2018
|
DOI | 10.1093/infdis/jiy370 |
Pubmed ID | |
Authors |
Hannah E Maier, Roger Lopez, Nery Sanchez, Sophia Ng, Lionel Gresh, Sergio Ojeda, Raquel Burger-Calderon, Guillermina Kuan, Eva Harris, Angel Balmaseda, Aubree Gordon |
Abstract |
Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly individuals. This work investigates the effect of obesity on the duration of viral shedding within household transmission studies in Managua, Nicaragua, over 3 seasons (2015-2017). Symptomatic obese adults were shown to shed influenza A virus 42% longer than nonobese adults (adjusted event time ratio [ETR], 1.42; 95% confidence interval [CI], 1.06-1.89); no association was observed with influenza B virus shedding duration. Even among paucisymptomatic and asymptomatic adults, obesity increased the influenza A shedding duration by 104% (adjusted ETR, 2.04; 95% CI, 1.35-3.09). These findings suggest that obesity may play an important role in influenza transmission. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 42 | 18% |
Japan | 16 | 7% |
United Kingdom | 11 | 5% |
Canada | 7 | 3% |
Brazil | 6 | 3% |
France | 5 | 2% |
Mexico | 5 | 2% |
Australia | 5 | 2% |
Switzerland | 5 | 2% |
Other | 29 | 12% |
Unknown | 109 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 188 | 78% |
Scientists | 25 | 10% |
Practitioners (doctors, other healthcare professionals) | 21 | 9% |
Science communicators (journalists, bloggers, editors) | 5 | 2% |
Unknown | 1 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 163 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 24 | 15% |
Researcher | 22 | 13% |
Student > Master | 17 | 10% |
Student > Ph. D. Student | 15 | 9% |
Other | 14 | 9% |
Other | 26 | 16% |
Unknown | 45 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 42 | 26% |
Immunology and Microbiology | 14 | 9% |
Biochemistry, Genetics and Molecular Biology | 10 | 6% |
Nursing and Health Professions | 8 | 5% |
Agricultural and Biological Sciences | 8 | 5% |
Other | 26 | 16% |
Unknown | 55 | 34% |