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Over-expression of phosphorylated mammalian target of rapamycin is associated with poor survival in oesophageal adenocarcinoma: a tissue microarray study

Overview of attention for article published in Journal of Clinical Pathology, November 2012
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Title
Over-expression of phosphorylated mammalian target of rapamycin is associated with poor survival in oesophageal adenocarcinoma: a tissue microarray study
Published in
Journal of Clinical Pathology, November 2012
DOI 10.1136/jclinpath-2012-201173
Pubmed ID
Authors

Margriet J D Prins, Roy J J Verhage, Jelle P Ruurda, Fiebo J W ten Kate, Richard van Hillegersberg

Abstract

Protein kinase mammalian target of rapamycin (mTOR) is an important downstream effector of the phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway. In several tumour types, phosphorylated mTOR (p-mTOR) over-expression is an independent prognostic marker for poor survival. However, p-mTOR expression has not been assessed in oesophageal adenocarcinoma (OAC).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 36%
Student > Master 2 14%
Researcher 2 14%
Professor 1 7%
Other 1 7%
Other 2 14%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 9 64%
Agricultural and Biological Sciences 2 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Unknown 2 14%