Title |
Flexible composition and execution of high performance, high fidelity multiscale biomedical simulations
|
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Published in |
Interface Focus, April 2013
|
DOI | 10.1098/rsfs.2012.0087 |
Pubmed ID | |
Authors |
D. Groen, J. Borgdorff, C. Bona-Casas, J. Hetherington, R. W. Nash, S. J. Zasada, I. Saverchenko, M. Mamonski, K. Kurowski, M. O. Bernabeu, A. G. Hoekstra, P. V. Coveney |
Abstract |
Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from laptops to petascale supercomputers, including combinations of these. Our work features two multiscale applications, in-stent restenosis and cerebrovascular bloodflow, which combine multiple existing single-scale applications to create a multiscale simulation. These applications can be efficiently coupled, deployed and executed on computers up to the largest (peta) scale, incurring a coupling overhead of 1-10% of the total execution time. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 7% |
Unknown | 42 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 27% |
Student > Ph. D. Student | 8 | 18% |
Professor > Associate Professor | 4 | 9% |
Student > Master | 4 | 9% |
Other | 3 | 7% |
Other | 8 | 18% |
Unknown | 6 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 13 | 29% |
Computer Science | 12 | 27% |
Physics and Astronomy | 4 | 9% |
Agricultural and Biological Sciences | 2 | 4% |
Chemistry | 2 | 4% |
Other | 3 | 7% |
Unknown | 9 | 20% |