Title |
Early surgery versus optimal current step-up practice for chronic pancreatitis (ESCAPE): design and rationale of a randomized trial
|
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Published in |
BMC Gastroenterology, March 2013
|
DOI | 10.1186/1471-230x-13-49 |
Pubmed ID | |
Authors |
Usama Ahmed Ali, Yama Issa, Marco J Bruno, Harry van Goor, Hjalmar van Santvoort, Olivier RC Busch, Cornelis HC Dejong, Vincent B Nieuwenhuijs, Casper H van Eijck, Hendrik M van Dullemen, Paul Fockens, Peter D Siersema, Dirk J Gouma, Jeanin E van Hooft, Yolande Keulemans, Jan W Poley, Robin Timmer, Marc G Besselink, Frank P Vleggaar, Oliver H Wilder-Smith, Hein G Gooszen, Marcel GW Dijkgraaf, Marja A Boermeester, for the Dutch Pancreatitis Study Group |
Abstract |
In current practice, patients with chronic pancreatitis undergo surgical intervention in a late stage of the disease, when conservative treatment and endoscopic interventions have failed. Recent evidence suggests that surgical intervention early on in the disease benefits patients in terms of better pain control and preservation of pancreatic function. Therefore, we designed a randomized controlled trial to evaluate the benefits, risks and costs of early surgical intervention compared to the current stepwise practice for chronic pancreatitis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 3 | 14% |
Netherlands | 2 | 9% |
United Kingdom | 2 | 9% |
United States | 2 | 9% |
Spain | 1 | 5% |
Colombia | 1 | 5% |
Switzerland | 1 | 5% |
Italy | 1 | 5% |
Portugal | 1 | 5% |
Other | 4 | 18% |
Unknown | 4 | 18% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 50% |
Practitioners (doctors, other healthcare professionals) | 7 | 32% |
Scientists | 3 | 14% |
Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
India | 1 | 1% |
Unknown | 94 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 15% |
Student > Master | 14 | 15% |
Other | 10 | 10% |
Student > Postgraduate | 8 | 8% |
Student > Bachelor | 6 | 6% |
Other | 21 | 22% |
Unknown | 23 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 54 | 56% |
Nursing and Health Professions | 4 | 4% |
Psychology | 2 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 1% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
Other | 5 | 5% |
Unknown | 29 | 30% |