Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections

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Article title
Combination Antifungal Therapy in the Treatment of <i>Scedosporium apiospermum</i> Central Nervous System Infections
Published in
Case Reports in Infectious Diseases
DOI 10.1155/2013/589490
Pubmed ID
Authors

Henao-Mart&#xed;nez, Andr&#xe9;s F.

Abstract

Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.

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