Title |
Transfusion-related acute lung injury: a clinical review
|
---|---|
Published in |
The Lancet, May 2013
|
DOI | 10.1016/s0140-6736(12)62197-7 |
Pubmed ID | |
Authors |
Alexander PJ Vlaar, Nicole P Juffermans |
Abstract |
Three decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, the US Food and Drug Administration acknowledge the syndrome as the leading cause of transfusion-related mortality. Understanding of the pathogenesis of TRALI has resulted in the design of preventive strategies from a blood-bank perspective. A major breakthrough in efforts to reduce the incidence of TRALI has been to exclude female donors of products with high plasma volume, resulting in a decrease of roughly two-thirds in incidence. However, this strategy has not completely eradicated the complication. In the past few years, research has identified patient-related risk factors for the onset of TRALI, which have empowered physicians to take an individualised approach to patients who need transfusion. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Malaysia | 2 | 14% |
India | 1 | 7% |
United States | 1 | 7% |
Ecuador | 1 | 7% |
Colombia | 1 | 7% |
Argentina | 1 | 7% |
United Kingdom | 1 | 7% |
Unknown | 6 | 43% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 64% |
Practitioners (doctors, other healthcare professionals) | 4 | 29% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 3 | <1% |
Colombia | 2 | <1% |
Brazil | 2 | <1% |
Chile | 1 | <1% |
Italy | 1 | <1% |
Panama | 1 | <1% |
Germany | 1 | <1% |
Netherlands | 1 | <1% |
Denmark | 1 | <1% |
Other | 2 | <1% |
Unknown | 307 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 52 | 16% |
Student > Postgraduate | 48 | 15% |
Researcher | 37 | 11% |
Student > Ph. D. Student | 31 | 10% |
Student > Master | 31 | 10% |
Other | 75 | 23% |
Unknown | 48 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 200 | 62% |
Agricultural and Biological Sciences | 11 | 3% |
Biochemistry, Genetics and Molecular Biology | 10 | 3% |
Veterinary Science and Veterinary Medicine | 6 | 2% |
Immunology and Microbiology | 5 | 2% |
Other | 30 | 9% |
Unknown | 60 | 19% |