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Chronopharmacology of Anti-Convulsive Therapy

Overview of attention for article published in Current Neurology and Neuroscience Reports, March 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

news
1 news outlet
wikipedia
3 Wikipedia pages
googleplus
1 Google+ user

Readers on

mendeley
84 Mendeley
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Title
Chronopharmacology of Anti-Convulsive Therapy
Published in
Current Neurology and Neuroscience Reports, March 2013
DOI 10.1007/s11910-013-0339-2
Pubmed ID
Authors

Sriram Ramgopal, Sigride Thome-Souza, Tobias Loddenkemper

Abstract

Approximately one-third of patients with epilepsy continue to have seizures despite antiepileptic therapy. Many seizures occur in diurnal, sleep/wake, circadian, or even monthly patterns. The relationship between biomarkers and state changes is still being investigated, but early results suggest that some of these patterns may be related to endogenous circadian patterns whereas others may be related to wakefulness and sleep or both. Chronotherapy, the application of treatment at times of greatest seizure susceptibility, is a technique that may optimize seizure control in selected patients. It may be used in the form of differential dosing, as preparations designed to deliver sustained or pulsatile drug delivery or in the form of 'zeitgebers' that shift endogenous rhythms. Early trials in epilepsy suggest that chronopharmacology may provide improved seizure control compared with conventional treatment in some patients. The present article reviews chronopharmacology in the treatment of epilepsy as well as future treatment avenues.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Denmark 1 1%
Unknown 81 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 19%
Student > Ph. D. Student 10 12%
Student > Bachelor 9 11%
Other 9 11%
Student > Postgraduate 9 11%
Other 17 20%
Unknown 14 17%
Readers by discipline Count As %
Medicine and Dentistry 23 27%
Neuroscience 11 13%
Pharmacology, Toxicology and Pharmaceutical Science 10 12%
Social Sciences 4 5%
Psychology 3 4%
Other 11 13%
Unknown 22 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 December 2023.
All research outputs
#2,689,244
of 22,710,079 outputs
Outputs from Current Neurology and Neuroscience Reports
#137
of 914 outputs
Outputs of similar age
#23,045
of 194,505 outputs
Outputs of similar age from Current Neurology and Neuroscience Reports
#2
of 9 outputs
Altmetric has tracked 22,710,079 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 914 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,505 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.