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Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study

Overview of attention for article published in PLOS Medicine, June 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

Mentioned by

news
4 news outlets
blogs
2 blogs
twitter
29 X users
facebook
12 Facebook pages
googleplus
1 Google+ user

Readers on

mendeley
188 Mendeley
citeulike
1 CiteULike
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Title
Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study
Published in
PLOS Medicine, June 2013
DOI 10.1371/journal.pmed.1001462
Pubmed ID
Authors

Irene Pichler, Fabiola Del Greco M., Martin Gögele, Christina M. Lill, Lars Bertram, Chuong B. Do, Nicholas Eriksson, Tatiana Foroud, Richard H. Myers, Michael Nalls, Margaux F. Keller, Beben Benyamin, John B. Whitfield, Peter P. Pramstaller, Andrew A. Hicks, John R. Thompson, Cosetta Minelli

Abstract

Although levels of iron are known to be increased in the brains of patients with Parkinson disease (PD), epidemiological evidence on a possible effect of iron blood levels on PD risk is inconclusive, with effects reported in opposite directions. Epidemiological studies suffer from problems of confounding and reverse causation, and mendelian randomization (MR) represents an alternative approach to provide unconfounded estimates of the effects of biomarkers on disease. We performed a MR study where genes known to modify iron levels were used as instruments to estimate the effect of iron on PD risk, based on estimates of the genetic effects on both iron and PD obtained from the largest sample meta-analyzed to date.

X Demographics

X Demographics

The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 188 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 3%
United Kingdom 3 2%
Italy 1 <1%
Ecuador 1 <1%
India 1 <1%
Spain 1 <1%
Canada 1 <1%
Unknown 174 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 43 23%
Student > Ph. D. Student 39 21%
Student > Bachelor 23 12%
Student > Master 13 7%
Other 11 6%
Other 35 19%
Unknown 24 13%
Readers by discipline Count As %
Medicine and Dentistry 50 27%
Agricultural and Biological Sciences 34 18%
Biochemistry, Genetics and Molecular Biology 23 12%
Neuroscience 12 6%
Economics, Econometrics and Finance 8 4%
Other 26 14%
Unknown 35 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 61. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2021.
All research outputs
#696,935
of 25,373,627 outputs
Outputs from PLOS Medicine
#1,104
of 5,162 outputs
Outputs of similar age
#5,155
of 209,898 outputs
Outputs of similar age from PLOS Medicine
#21
of 70 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,162 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 77.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,898 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.