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Monitoring Prednisolone and Prednisone in Saliva

Overview of attention for article published in Therapeutic Drug Monitoring, August 2013
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Title
Monitoring Prednisolone and Prednisone in Saliva
Published in
Therapeutic Drug Monitoring, August 2013
DOI 10.1097/ftd.0b013e3182899ea2
Pubmed ID
Authors

Nynke Teeninga, Zheng Guan, Jan Freijer, An F. C. Ruiter, Mariëtte T. Ackermans, Joana E. Kist-van Holthe, Teun van Gelder, Jeroen Nauta

Abstract

Prednisolone (PLN) is a widely used corticosteroid in a variety of immune-mediated diseases. Treatment regimes generally consist of empirically derived treatment doses, whereas therapeutic response among patients is highly variable. Drug monitoring of serum PLN levels might support a more rational approach to dose selection, yet is invasive and laborious. In analogy to cortisol, salivary PLN may offer a good alternative for serum PLN, being a representative approximation of free serum PLN. The aims of this study were to evaluate the correlation between free serum and salivary PLN levels and to quantify this relationship within a population pharmacokinetic model.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 27%
Student > Master 3 14%
Student > Doctoral Student 2 9%
Lecturer 1 5%
Other 1 5%
Other 4 18%
Unknown 5 23%
Readers by discipline Count As %
Medicine and Dentistry 9 41%
Biochemistry, Genetics and Molecular Biology 2 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Nursing and Health Professions 1 5%
Social Sciences 1 5%
Other 3 14%
Unknown 4 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2013.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Therapeutic Drug Monitoring
#1,107
of 1,787 outputs
Outputs of similar age
#132,644
of 210,078 outputs
Outputs of similar age from Therapeutic Drug Monitoring
#7
of 17 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,787 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,078 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.